DeepATT DeepATT is a model for identifying functional effects of DNA sequences.

Introduction

DeepATT is a model for identifying functional effects of DNA sequences. This is implemented by tensorflow-2.0. Our model has four built-in neural network constructions: convolution layer captures regulatory motifs, recurrent layer captures a regulatory grammar, category attention layer (improved from self-attention layer) selects corresponding valid features for different functions, and category dense layer (improved from local-connected dense layer) classifies the labels with feature vectors selected by the query vectors of the regulatory functions. We compare DeepATT with DeepSEA and DanQ, which are all implemented or replicated on our own platform. Comparison results demonstrate that DeepATT achieves state-of-the-art performance of 0.94519 AV-AUROC and 0.39522 AV-AUPR, which is far better than other non-coding DNA regulatory function prediction methods.

Publications

  1. DeepATT: a hybrid category attention neural network for identifying functional effects of DNA sequences
    Cite this
    Jiawei Li, Yuqian Pu, Jijun Tang, Quan Zou, Fei Guo, May 2021 - Briefings in Bioinformatics

Credits

  1. Fei Guo fguo@tju.edu.cn
    Investigator

    School of Computer Science and Technology, College of Intelligence and Computing, Tianjin University, China

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Summary
AccessionBT007148
Tool TypeApplication
Category
PlatformsLinux/Unix
TechnologiesPython3
User InterfaceTerminal Command Line
Latest Release1.0 (May 31, 2021)
Download Count831
Country/RegionChina
Submitted ByFei Guo
Fundings

2018YFC0910400