MIRS MIRS is a prognostic prediction tool

Current scoring systems for prognostic of breast cancer are avilable but usually consider only one prognostic feature. We aim to develop a novel prognostic scoring system based on both immune-infiltration and metastasis features to not only assess the patient prognoses more accurately but also guide therapy for patients with breast cancer. Computational immune-infiltration and gene profiling analysis identified a 12-gene panel firstly characterizing immune-infiltrating and metastatic features. Neural network model yielded a precise prognostic scoring system called metastatic and immunogenomic risk score (MIRS). MIRS could effectively improve the accuracy of prognosis for patients with breast cancer. Also, MIRS is a useful webtool, which is deposited at http://Iva85.github.io/MIRS/, to help clinicians in designing personalized therapies for patients with breast cancer.