inMTSCCA pcMTSCCA、hocMTSCCA

 Identifying genetic risk factors for Alzheimer’s disease (AD) is an important research topic, in this work, we propose two integrated multi-task sparse canonical correlation analysis (MTSCCA) methods to identify genetic factors  as well as AD-relevant endophenotypic markers. These two MTSCCA methods, called the pairwise endophenotype correlation guided MTSCCA (pcMTSCCA) and the high-order endophenotype correlation guided MTSCCA (hocMTSCCA). Our methods provided very helpful clues for further in-depth investigation and thus were powerful in multi-omics heterogeneous markers identification.

# integratedMTSCCA

TItle:

inMTSCCA: An Integrated Multi-task Sparse Canonical Correlation Analysis for Multi-omics Brain Imaging Genetics

- the pairwise endophenotype correlation guided MTSCCA (*pc*MTSCCA)

- the high-order endophenotype correlation guided MTSCCA (*hoc*MTSCCA)

Code:

Unzip tensor_toolbox-master.zip and run example.m to get the results.

Please contact Lei Du (dulei@nwpu.edu.cn) and Jin Zhang(jinzhang@mail.nwpu.edu.cn) for any comments or questions.