项目编号 PRJCA001908
项目标题 Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer
涉及领域 Medical
数据类型 Transcriptome or Gene expression
物种名称 Mus musculus
描述信息 Here we report a single cell based transcriptomic profiling study on various types of cells across every pathogenic stage during ESCC initiation and development in a mouse model induced by 4NQO.
样品范围 Multispecies
发布日期 2023-03-27
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
32709844 Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer Nature Communications 10.1038/s41467-020-17492-y 2020
39550363 Temporal single-cell RNA sequencing dataset of gastroesophagus development from embryonic to post-natal stages Scientific Data 10.1038/s41597-024-04081-7 2024
38452871 Autophagy Contributes to Homeostasis in Esophageal Epithelium Where High Autophagic Vesicle Level Marks Basal Cells With Limited Proliferation and Enhanced Self-Renewal Potential Cellular and Molecular Gastroenterology and Hepatology 10.1016/j.jcmgh.2024.02.018 2024
34365093 Transcriptomics based multi-dimensional characterization and drug screen in esophageal squamous cell carcinoma EBioMedicine 10.1016/j.ebiom.2021.103510 2021
38594232 Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis Nature Communications 10.1038/s41467-024-47173-z 2024
36672394 A Systemic and Integrated Analysis of p63-Driven Regulatory Networks in Mouse Oral Squamous Cell Carcinoma Cancers 10.3390/cancers15020446 2023
38516269 Lymphatic endothelial cell-mediated accumulation of CD177 + Treg cells suppresses antitumor immunity in human esophageal squamous cell carcinoma Oncoimmunology 10.1080/2162402X.2024.2327692 2024
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
National Natural Science Foundation of China (NSFC) 81725015
National Natural Science Foundation of China (NSFC) 21675098
National Natural Science Foundation of China (NSFC) 21525521
National Natural Science Foundation of China (NSFC) 21927802
Medical and Health Technology Innovation Project of Chinese Academy of Medical Sciences 2016I2M3019
Medical and Health Technology Innovation Project of Chinese Academy of Medical Sciences 2016I2M4002
Medical and Health Technology Innovation Project of Chinese Academy of Medical Sciences 2019I2M2001
Beijing Outstanding Young Scientist Program BJJWZYJH01201910023027
2018 Beijing Brain Initiative Z181100001518004
提交者 Yamei Chen (linslab@163.com)
提交单位 Cancer Hospital, Chinese Academy of Medical Sciences
提交日期 2019-11-13

项目包含数据信息

资源名称 描述
BioSample (21)  show -
GSA (1) -
CRA002118 Single cell RNA sequencing of multistep ESCC mouse model