| Accession |
PRJCA002164 |
| Title |
Global Immune Characterization of Hepatocellular Carcinoma Identifies Macrophage and T cell Subsets Associated with Disease Progression |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
Diverse immune cells in the tumor microenvironment form a complex ecosystem, but our knowledge of their heterogeneity and dynamics within hepatocellular carcinoma (HCC) remains poorly understood. We assess the variability and phenotypes of immune cells within HCC microenvironment by performing single-cell RNA sequencing on 41,698 immune cells from 7 pairs of HCC tumors and nontumor liver tissues. |
| Sample scope |
Single cell |
| Release date |
2020-01-25 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 33298893
|
Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression
|
Cell Discovery
|
10.1038/s41421-020-00214-5
|
2020
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
91859105
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81961128025
|
|
| Basic Research Project from Technology Commission of Shanghai Municipality
|
|
17JC1402200
|
|
|
|
| Submitter |
song
guo
he (docsong2013@163.com)
|
| Organization |
Fudan University |
| Submission date |
2020-01-25 |
