项目编号 PRJCA002771
项目标题 Dissecting the epigenomic dynamics of human fetal germ cell development at single-cell resolution
涉及领域 Medical
数据类型 Whole genome sequencing
Raw sequence reads
物种名称 Homo sapiens
描述信息 Proper development of fetal germ cells (FGCs) is vital for the precise transmission of genetic and epigenetic information through generations. The transcriptional landscapes of human FGC development have been revealed; however, the epigenetic reprogramming process of FGCs remains elusive. Here, we profiled the genome-wide DNA methylation and chromatin accessibility of human FGCs at different phases as well as gonadal niche cells at single-cell resolution. Our single-cell epigenomic atlas as well as functional assay provide valuable insights for understanding the strongly heterogeneous, unsynchronized, yet highly robust nature of human germline cell development.
样品范围 Single cell
发布日期 2022-01-02
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
Beijing Advanced Innovation Center for Genomics N/A N/A N/A
提交者 Fuchou Tang (tangfuchou@pku.edu.cn)
提交单位 Peking University
提交日期 2020-05-31

项目包含数据信息

资源名称 描述
BioSample (825)  show -