| Accession |
PRJCA003693 |
| Title |
Immune Cells Landscape of Sexual Dimorphism and Aging by Single-cell transcriptomic analysis |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
Differences in immune function and responses contribute to life-span disparities between sexes, which also contain the different cellular plasticity in response to aging. However, the sexual dimorphism and cell plasticity influenced by aging remain elusive. We profiled circulating immune cells obtained from males and females both in young and old group at single-cell resolution and constructed a precise atlas of human blood circulating immune cells. |
| Sample scope |
Single cell |
| Release date |
2021-08-06 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 34385315
|
Effects of sex and aging on the immune cell landscape as assessed by single-cell transcriptomic analysis
|
Proceedings of the National Academy of Sciences of the United States of America
|
10.1073/pnas.2023216118
|
2021
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| National Natural Science Foundation of China (NSFC)
|
|
81670897
|
|
| the National Key R&D Program of China
|
|
2017YFA0105800
|
|
|
|
| Submitter |
Wenru
Su (suwr3@mail.sysu.edu.cn)
|
| Organization |
Zhongshan Ophthalmic Center,Sun Yat-sen University |
| Submission date |
2020-10-19 |
