| 项目编号 |
PRJCA003827 |
| 项目标题 |
A Single-Cell Transcriptomic Atlas of Human Skin Aging |
| 涉及领域 |
Model organism |
| 数据类型 |
Transcriptome or Gene expression
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
To obtain the first aging atlas of human skin, we systematically analyzed 35,678 cells of skin sampled from young,middle and old human eyelid. Systemic effects of aging on different skin cell types were evaluated in terms of cell-type composition, cell-specific molecular programs, transcription factors network. |
| 样品范围 |
Single cell |
| 发布日期 |
2022-02-08 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 36514051
|
Microbiota-host crosstalk in the newborn and adult rumen at single-cell resolution
|
BMC Biology
|
10.1186/s12915-022-01490-1
|
2022
|
| 40898171
|
A single-cell transcriptome atlas of pig skin reveals cellular heterogeneity from embryonic development to postnatal aging
|
BMC Biology
|
10.1186/s12915-025-02390-w
|
2025
|
| 34939928
|
Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage Editor's evaluation Decision letter Author response
|
eLife
|
10.7554/eLife.71052
|
2021
|
| 39987255
|
Unveiling the cell-type-specific landscape of cellular senescence through single-cell transcriptomics using SenePy
|
Nature Communications
|
10.1038/s41467-025-57047-7
|
2025
|
| 41162753
|
Distinct senotypes in p16- and p21-positive cells across human and mouse aging tissues
|
The EMBO Journal
|
10.1038/s44318-025-00601-2
|
2025
|
| 40585982
|
Endothelium-specific sensing of mechanical signals drives epidermal aging through coordinating retinoid metabolism
|
Theranostics
|
10.7150/thno.112299
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Chinese Academy of Sciences (CAS)
|
National Key Research and Development Program of China
|
2018YFC2000100
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2017YFA0103300
|
|
|
|
| 提交者 |
Guanghui
Liu (ghliu@ioz.ac.cn)
|
| 提交单位 |
Institute of Zoology, Chinese Academy of Sciences |
| 提交日期 |
2020-11-05 |
