项目编号 PRJCA004466
项目标题 Generation and Characterization of Stable Pig Pre-Gastrulation Epiblast Stem Cell Lines
涉及领域 Agricultural
数据类型 Whole genome sequencing
Epigenomics
Transcriptome or Gene expression
Raw sequence reads
物种名称 Sus scrofa
描述信息 single-cell RNA-sequencing profiling of porcine preimplantation embryos from embryonic day (E) 0 to E14, we successfully developed an in vitro culture system for establishing and maintaining stable pluripotent stem cell lines from porcine E10 pre-gastrulation epiblasts (termed pgEpiSCs).ultra-deep in situ Hi-C analysis of the pgEpiSCs and porcine embryonic fibroblast revealed functional impacts of 3D-spatial associations on the transcriptional regulation of pluripotency marker genes.
样品范围 Monoisolate
发布日期 2021-12-02
出版信息
PubMed ID 文章标题 杂志名称 Doi 发表年份
34848870 Generation and characterization of stable pig pregastrulation epiblast stem cell lines Cell Research 10.1038/s41422-021-00592-9 2022
项目资金来源
机构 项目类型 授权项目ID 授权项目名称
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2018YFC1003100
Chinese Academy of Sciences (CAS) Youth Innovation Promotion Association 2020104
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2019YFA0110700
Ministry of Science and Technology of the People's Republic of China (MOST) International (Regional) Joint Research Programs 2020YFA0113200
Chinese Academy of Sciences (CAS) General Program 2021081
National Natural Science Foundation of China (NSFC) General Program 31970825
National Natural Science Foundation of China (NSFC) General Program 31772601
National Natural Science Foundation of China (NSFC) General Program 31601941
National Natural Science Foundation of China (NSFC) General Program 31571497
Beijing Natural Science Foundation 6192005
Plan 111 B12008
Research Programs from the State Key Laboratories for Agro-biotechnology, China Agricultural University 2020SKLAB1-3
Ministry of Science and Technology of the People's Republic of China (MOST) National Key Technologies R&D Program 2020YFA0509500
National Natural Science Foundation of China (NSFC) International (Regional) Joint Research Programs U19A2036
National Natural Science Foundation of China (NSFC) General Program 31772576
the Science and Technology Program of Sichuan 2021YFYZ0009
提交者 Caihong Zheng (zhengch@big.ac.cn)
提交单位 Beijing Institute of Genomics, Chinese Academy of Sciences
提交日期 2021-02-07

项目包含数据信息

资源名称 描述
BioSample (3) -
SAMC341726 pEFs
SAMC341725 pgEpiSCs
SAMC341724 pEmbryo
GSA (1) -
CRA003960 Generation and characterization of stable porcine pre-gastrulation epiblast stem cell lines