Accession | PRJCA004901 | ||||||||
---|---|---|---|---|---|---|---|---|---|
Title | Study on carcinogenesis mechanism of esophageal cancer and gastric cardiac adenocarcinoma | ||||||||
Relevance | Medical | ||||||||
Data types | Whole genome sequencing | ||||||||
Organisms | Homo sapiens | ||||||||
Description | In this project, we investigated the availability and function of extrachromosomal DNA in the gastric cardia adenocarcinoma (GCA) from a Chinese cohort of gastric cardia adenocarcinoma with whole-genome sequencing (WGS), whole-exome sequencing (WES), and immunohistochemistry. For the first time, we identified the ecDNA amplicons present in most GCA patients, and found that some oncogenes are present as ecDNA amplicons in these patients. | ||||||||
Sample scope | Monoisolate | ||||||||
Release date | 2021-04-29 | ||||||||
Grants |
|
||||||||
Submitter | Li Dong Wang (ldwang2007@126.com) | ||||||||
Organization | Zhengzhou University | ||||||||
Submission date | 2021-04-28 |
Resource name | Description |
---|---|
BioSample (72) show | - |