Accession PRJCA004901
Title Study on carcinogenesis mechanism of esophageal cancer and gastric cardiac adenocarcinoma
Relevance Medical
Data types Whole genome sequencing
Organisms Homo sapiens
Description In this project, we investigated the availability and function of extrachromosomal DNA in the gastric cardia adenocarcinoma (GCA) from a Chinese cohort of gastric cardia adenocarcinoma with whole-genome sequencing (WGS), whole-exome sequencing (WES), and immunohistochemistry. For the first time, we identified the ecDNA amplicons present in most GCA patients, and found that some oncogenes are present as ecDNA amplicons in these patients.
Sample scope Monoisolate
Release date 2021-04-29
Grants
Agency program Grant ID Grant title
Ministry of Science and Technology of the People's Republic of China (MOST) 2016YFC0901403
Submitter Li Dong Wang (ldwang2007@126.com)
Organization Zhengzhou University
Submission date 2021-04-28

Project Data

Resource name Description
BioSample (72)  show -