| 项目编号 |
PRJCA005369 |
| 项目标题 |
Targeted-NGS of circulating tumor DNA, bone marrow and peripheral blood mononuclear cells in pediatric AML |
| 涉及领域 |
pediatric AML |
| 数据类型 |
Raw sequence reads
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
The aim of the study was to validate the diagnostic role of circulating tumor DNA (ctDNA) in genetics aberration on basis of next-generation sequencing (NGS) in pediatric acute myeloid leukemia (AML).Bone marrow (BM) and peripheral blood (PB) were collected from 20 AML children at the time of initial diagnosis, and ctDNA sample was isolated from PB. Detection of mutation was performed on ctDNA, BM and peripheral blood mononuclear cell (PBMC) by NGS based on a 185-gene panel. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2021-06-04 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 34422630
|
Targeted Next-Generation Sequencing of Circulating Tumor DNA, Bone Marrow, and Peripheral Blood Mononuclear Cells in Pediatric AML
|
Frontiers in Oncology
|
10.3389/fonc.2021.666470
|
2021
|
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| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| No funding support
|
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|
|
| 提交者 |
Xiaofan
Zhu (xfzhu@ihcams.ac.cn)
|
| 提交单位 |
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College |
| 提交日期 |
2021-06-04 |
