| Accession |
PRJCA005369 |
| Title |
Targeted-NGS of circulating tumor DNA, bone marrow and peripheral blood mononuclear cells in pediatric AML |
| Relevance |
pediatric AML |
| Data types |
Raw sequence reads
|
| Organisms |
Homo sapiens
|
| Description |
The aim of the study was to validate the diagnostic role of circulating tumor DNA (ctDNA) in genetics aberration on basis of next-generation sequencing (NGS) in pediatric acute myeloid leukemia (AML).Bone marrow (BM) and peripheral blood (PB) were collected from 20 AML children at the time of initial diagnosis, and ctDNA sample was isolated from PB. Detection of mutation was performed on ctDNA, BM and peripheral blood mononuclear cell (PBMC) by NGS based on a 185-gene panel. |
| Sample scope |
Multiisolate |
| Release date |
2021-06-04 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 34422630
|
Targeted Next-Generation Sequencing of Circulating Tumor DNA, Bone Marrow, and Peripheral Blood Mononuclear Cells in Pediatric AML
|
Frontiers in Oncology
|
10.3389/fonc.2021.666470
|
2021
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| No funding support
|
|
|
|
|
|
| Submitter |
Xiaofan
Zhu (xfzhu@ihcams.ac.cn)
|
| Organization |
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College |
| Submission date |
2021-06-04 |
