| Accession |
PRJCA005554 |
| Title |
advanced renal cell carcinoma with tumor thrombus single-cell |
| Relevance |
Medical |
| Data types |
Transcriptome or Gene expression
|
| Organisms |
Homo sapiens
|
| Description |
To systematically explore the complete tumor ecosystem heterogeneity at a single-cell level in primary tumor and paired tumor thrombus. A total of 22 surgically resected tissue samples were collected from patients with advanced renal cell carcinoma, which including primary tumors (n=9), paired tumor thrombus (n=9) and adjacent renal tissues (n=4). Cell capture and cDNA synthesis were carried out in 10X Genomics platform, and then transcriptome sequencing was performed in NovaSeq 6000 platform after meeting the all quality control. |
| Sample scope |
Single cell |
| Release date |
2022-04-01 |
| Publication |
| PubMed ID |
Article title |
Journal name |
DOI |
Year |
| 35361264
|
Decoding the multicellular ecosystem of vena caval tumor thrombus in clear cell renal cell carcinoma by single-cell RNA sequencing
|
Genome Biology
|
10.1186/s13059-022-02651-9
|
2022
|
|
|
| Grants |
| Agency |
program |
Grant ID |
Grant title |
| Chinese Academy of Sciences (CAS)
|
Strategic Priority Research Program of Chinese Academy of Sciences (CAS)
|
XDA16010102
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2018YFC2000100
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key Technologies R&D Program
|
2019YFA0110900
|
|
| Chinese Academy of Sciences (CAS)
|
|
QYZDB-SSW-SMC039
|
|
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81672541
|
|
|
|
| Submitter |
Weimin
ci (ciwm@big.ac.cn)
|
| Organization |
Beijing Institute of Genomics, Chinese Academy of Sciences |
| Submission date |
2021-06-21 |
