Accession PRJCA008266
Title Maintenance and reconstruction of male fertility
Relevance Medical
Data types Epigenomics
Phenotype or Genotype
Transcriptome or Gene expression
Single cell sequencing
Organisms Mus musculus
Homo sapiens
Description This project aim to elucidate the key regulatory mechanism of pluripotent stem cell directional differentiation into functional cells like leydig cell, and explore the interaction between stem leydig cell and male germline stem cells.The maintenance and reconstruction of male fertility can be achieved in primate models by transplanting pluripotent stem cell-derived stem leydig cell, which provides support for the feasibility of using stem leydig cell to reconstruct male fertility in clinic.
Sample scope Multispecies
Release date 2022-05-11
Publication
PubMed ID Article title Journal name DOI Year
34432948
32973147
31530567
32875102
33060592
31037131
34453037
Grants
Agency program Grant ID Grant title
National Key Research and Development Program of China 2017YFA0103802
Submitter Huang Xiaojia (huangxj47@mail2.sysu.edu.cn)
Organization Sun Yat-sen University
Submission date 2022-02-15

Project Data

Resource name Description
BioSample (52)  show -
GSA (1) -
CRA006198 scRNA-seq of Testis Interstitial cells during aging