| 项目编号 |
PRJCA009009 |
| 项目标题 |
single cell transcriptomics unveils the defects of endometriosis |
| 涉及领域 |
Medical |
| 数据类型 |
Transcriptome or Gene expression
Single cell sequencing
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
Endometriosis is a prevalent gynecological disease that bother 10% of women at reproductive age. There are different types of endometriosis, among which the ovarian endometriosis is the most prevalent. Despite the influence, the pathogenic mechanism of ovarian endometriosis is under exploration. The major barrier of the study is the minimal pathogenic cell number at the ectopic site of ovary. Here we took advantage of single-cell transcriptomic sequencing technology, sequenced samples from endometriosis patients and healthy controls. We took samples both from endometrial tissues and ovarian lesions, also normal endometrial tissues from healthy controls. |
| 样品范围 |
Single cell |
| 发布日期 |
2024-01-25 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40622575
|
Organoids as powerful models of endometrium epithelium in transcriptomic, cellular and functional mimicry
|
Cellular and Molecular Life Sciences
|
10.1007/s00018-025-05807-5
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Beijing Advanced Innovation Center for Genomics (ICG)
|
|
N/A
|
|
|
|
| 提交者 |
Fuchou
Tang (tangfuchou@pku.edu.cn)
|
| 提交单位 |
Peking University |
| 提交日期 |
2022-04-06 |
