| 项目编号 |
PRJCA015974 |
| 项目标题 |
Single-cell and spatial transcriptomic profiling of human glioblastomas |
| 涉及领域 |
Medical |
| 数据类型 |
Single cell sequencing
|
| 物种名称 |
Mus musculus
Homo sapiens
|
| 描述信息 |
This deposition includes scRNA-seq and Spatial Transcriptomics data for 24 GBM patients, scRNA-seq and bulk RNA-seq data for both wild-type (WT) and SiglecE knockout (KO) mice bearing intracranial CT2A glioma. |
| 样品范围 |
Multispecies |
| 发布日期 |
2024-02-18 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 37460871
|
Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response
|
Nature Cancer
|
10.1038/s43018-023-00598-9
|
2023
|
| 41174767
|
Spatial-reprogramming derived GPNMB+ macrophages interact with COL6A3+ fibroblasts to enhance vascular fibrosis in glioblastoma
|
Genome Medicine
|
10.1186/s13073-025-01553-2
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
National Key R&D Program of China
|
2019YFA0110300
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82203538
|
|
| National Natural Science Foundation of China (NSFC)
|
|
82150117
|
|
| Ministry of Science and Technology of the People's Republic of China (MOST)
|
|
2020YFA0509400
|
|
| National Natural Science Foundation of China (NSFC)
|
|
81972668
|
|
| National Natural Science Foundation of China (NSFC)
|
|
31900570
|
|
|
|
| 提交者 |
Guangshuai
Jia (guangshuaijia@icloud.com)
|
| 提交单位 |
Guangzhou Medical University |
| 提交日期 |
2023-03-31 |
