| 项目编号 | PRJCA017165 | ||||||||||||||||||||
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| 项目标题 | substate transitions of reactive astrocytes | ||||||||||||||||||||
| 涉及领域 | Model organism | ||||||||||||||||||||
| 数据类型 | proteome | ||||||||||||||||||||
| 物种名称 | Mus musculus | ||||||||||||||||||||
| 描述信息 | Reactive astrocytes play important roles in brain injury, stroke, neurodegenerative diseases, and aging. Traditionally, they have been classified into neurotoxic (A1) and neuroprotective (A2) subtypes based on disease conditions and gene expression patterns. In this study, we reported a consistent progression from a nonreactive state to a neuroprotective substate, and ultimately to a neurotoxic substate in astrocytes when exposed to inflammatory stimuli. | ||||||||||||||||||||
| 样品范围 | Monoisolate | ||||||||||||||||||||
| 发布日期 | 2024-11-20 | ||||||||||||||||||||
| 出版信息 |
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| 项目资金来源 |
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| 提交者 | Zhengzheng Xu (zzxu@ion.ac.cn) | ||||||||||||||||||||
| 提交单位 | institute of neuronscience, CAS | ||||||||||||||||||||
| 提交日期 | 2023-05-22 |