| Accession | PRJCA017165 | ||||||||||||||||||||
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| Title | substate transitions of reactive astrocytes | ||||||||||||||||||||
| Relevance | Model organism | ||||||||||||||||||||
| Data types | proteome | ||||||||||||||||||||
| Organisms | Mus musculus | ||||||||||||||||||||
| Description | Reactive astrocytes play important roles in brain injury, stroke, neurodegenerative diseases, and aging. Traditionally, they have been classified into neurotoxic (A1) and neuroprotective (A2) subtypes based on disease conditions and gene expression patterns. In this study, we reported a consistent progression from a nonreactive state to a neuroprotective substate, and ultimately to a neurotoxic substate in astrocytes when exposed to inflammatory stimuli. | ||||||||||||||||||||
| Sample scope | Monoisolate | ||||||||||||||||||||
| Release date | 2024-11-20 | ||||||||||||||||||||
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| Submitter | Zhengzheng Xu (zzxu@ion.ac.cn) | ||||||||||||||||||||
| Organization | institute of neuronscience, CAS | ||||||||||||||||||||
| Submission date | 2023-05-22 |