| 项目编号 |
PRJCA018406 |
| 项目标题 |
HBV integration in pancreatic cancer |
| 涉及领域 |
Medical |
| 数据类型 |
Raw sequence reads
|
| 物种名称 |
Homo sapiens
|
| 描述信息 |
By using a high-throughput viral integration detection approach (HIVID), a total of 425 HBV integration sites are identified, among which mixed lineage leukemia gene 4 (MLL4) is found to be repeatedly targeted by HBV in both HCC and PDAC. We identify a critical role for MLL4 in promoting PDAC growth and metastasis. |
| 样品范围 |
Multiisolate |
| 发布日期 |
2025-07-16 |
| 出版信息 |
| PubMed ID |
文章标题 |
杂志名称 |
Doi |
发表年份 |
| 40741875
|
Analysis of hepatitis B virus integration identifies KMT2B as a novel cancer‐related gene in pancreatic cancer
|
Clinical and Translational Medicine
|
10.1002/ctm2.70424
|
2025
|
|
|
| 项目资金来源 |
| 机构 |
项目类型 |
授权项目ID |
授权项目名称 |
| National Natural Science Foundation of China (NSFC)
|
General Program
|
81572312
|
|
|
|
| 提交者 |
Hong
Tu (tuhong@shsci.org)
|
| 提交单位 |
Renji Hospital, Shanghai Jiao Tong University School of Medicine |
| 提交日期 |
2023-07-16 |
