样本编号	SAMC2998802
外部数据库编号	GSA-Human: HRS905640
样品名称	17N
样本标题	para-tumor of patient 17
样品类型	Human sample
物种名称	Homo sapiens
描述信息	para-tumor of patient 17 with HBV infection
样本属性	*该样本包含更多受控访问信息，请通过GSA-Human系统申请项目HRA005175数据获取。
发布日期	2025-07-28
项目编号	PRJCA018406
提交者	Hong Tu (tuhong@shsci.org)
提交单位	Renji Hospital, Shanghai Jiao Tong University School of Medicine
提交日期	2023-08-12

样本包含数据信息

资源名称	描述
GSA-Human (1)	-
HRA005175 (Controlled Access)	Hepatitis B virus (HBV) infection has been reported to be associated with pancreatic ductal adenocarcinoma (PDAC). However, the evidence is limited to the epidemiological study. There is still no evidence showing the HBV infection and integration in PDAC cells. Here, we report that HBV DNA is detected in 26.74% (23/86) of the PDAC tissues. Furthermore, by using a high-throughput viral integration detection approach (HIVID), a total of 425 HBV integration sites are identified, among which mixed lineage leukemia gene 4 (MLL4) is found to be repeatedly targeted by HBV in both HCC and PDAC.

资源名称

描述

GSA-Human (1)

HRA005175 (Controlled Access)

Hepatitis B virus (HBV) infection has been reported to be associated with pancreatic ductal adenocarcinoma (PDAC). However, the evidence is limited to the epidemiological study. There is still no evidence showing the HBV infection and integration in PDAC cells. Here, we report that HBV DNA is detected in 26.74% (23/86) of the PDAC tissues. Furthermore, by using a high-throughput viral integration detection approach (HIVID), a total of 425 HBV integration sites are identified, among which mixed lineage leukemia gene 4 (MLL4) is found to be repeatedly targeted by HBV in both HCC and PDAC.