项目编号

PRJCA024234

项目标题

Identification of KRAS mutation-associated gut microbiota in colorectal cancer and construction of predictive machine learning model

涉及领域

Medical

数据类型

Metagenome

物种名称

human gut metagenome

描述信息

This study aimed to identify differential gut microbiota between KRAS mutant and KRAS wild-type CRC patients by fecal 16S rRNA gene sequencing. We intend to analyze their correlations with immune infiltrating cells, immune-related genes and enriched biological functions, all of which will be derived from the analysis of mRNA sequencing data, aiming to demystify their roles in KRAS mutation and the progression of CRC. Moreover, we will employ these KRAS mutation-associated gut microbiota to construct a predictive machine learning model, offering fresh insights into for microbiological discovery and clinical prediction of KRAS mutation status for CRC patients.

样品范围

Environment

发布日期

2024-03-12

出版信息

PubMed ID	文章标题	杂志名称	Doi	发表年份
38572984	Identification of KRAS mutation-associated gut microbiota in colorectal cancer and construction of predictive machine learning model	Microbiology Spectrum	10.1128/spectrum.02720-23	2024

项目资金来源

机构	项目类型	授权项目ID	授权项目名称
Natural Science Foundation of Guangxi Province (Guangxi Natural Science Foundation)		2021GXNSFAA196008
Youth Science Foundation of Guangxi Medical University		GXMUYSF202402
Youth Research Project of Guangxi Medical University Affiliated Cancer Hospital		yuanqingji2023-10hao
Middle-aged and Young Teachers' Basic Ability Promotion Project of Guangxi (Basic Ability Promotion Project of Guangxi)		2021KY0087
China Postdoctoral Science Foundation		2023MD734155
Youth Science Foundation of Guangxi Medical University		GXMUYSF202357
Guangxi Key Laboratory of Basic and Translational Research for Colorectal Cancer		N/A

提交者

Weizhong Tang (tangweizhong@gxmu.edu.cn)

提交单位

Guangxi Medical University Cancer Hospital

提交日期

2024-03-12

项目包含数据信息

资源名称	描述
BioSample (94) show	-
SAMC3437870	16sRNA sequencing of colorectal cancer patient: stool S0239
SAMC3437869	16sRNA sequencing of colorectal cancer patient: stool M0240
SAMC3437868	16sRNA sequencing of colorectal cancer patient: stool F290
SAMC3437867	16sRNA sequencing of colorectal cancer patient: stool F287
SAMC3437866	16sRNA sequencing of colorectal cancer patient: stool F286
SAMC3437865	16sRNA sequencing of colorectal cancer patient: stool F285
SAMC3437864	16sRNA sequencing of colorectal cancer patient: stool F281
SAMC3437863	16sRNA sequencing of colorectal cancer patient: stool F277
SAMC3437862	16sRNA sequencing of colorectal cancer patient: stool F272
SAMC3437861	16sRNA sequencing of colorectal cancer patient: stool F269
SAMC3437860	16sRNA sequencing of colorectal cancer patient: stool F265
SAMC3437859	16sRNA sequencing of colorectal cancer patient: stool F262
SAMC3437858	16sRNA sequencing of colorectal cancer patient: stool F259
SAMC3437857	16sRNA sequencing of colorectal cancer patient: stool F255
SAMC3437856	16sRNA sequencing of colorectal cancer patient: stool F254
SAMC3437855	16sRNA sequencing of colorectal cancer patient: stool F246
SAMC3437854	16sRNA sequencing of colorectal cancer patient: stool F244
SAMC3437853	16sRNA sequencing of colorectal cancer patient: stool F243
SAMC3437852	16sRNA sequencing of colorectal cancer patient: stool F240
SAMC3437851	16sRNA sequencing of colorectal cancer patient: stool F234
SAMC3437850	16sRNA sequencing of colorectal cancer patient: stool F232
SAMC3437849	16sRNA sequencing of colorectal cancer patient: stool F230
SAMC3437848	16sRNA sequencing of colorectal cancer patient: stool F224
SAMC3437847	16sRNA sequencing of colorectal cancer patient: stool F221
SAMC3437846	16sRNA sequencing of colorectal cancer patient: stool F220
SAMC3437845	16sRNA sequencing of colorectal cancer patient: stool F216
SAMC3437844	16sRNA sequencing of colorectal cancer patient: stool F212
SAMC3437843	16sRNA sequencing of colorectal cancer patient: stool F210
SAMC3437842	16sRNA sequencing of colorectal cancer patient: stool F208
SAMC3437841	16sRNA sequencing of colorectal cancer patient: stool F205
SAMC3437840	16sRNA sequencing of colorectal cancer patient: stool F203
SAMC3437839	16sRNA sequencing of colorectal cancer patient: stool F199
SAMC3437838	16sRNA sequencing of colorectal cancer patient: stool F198
SAMC3437837	16sRNA sequencing of colorectal cancer patient: stool F197
SAMC3437836	16sRNA sequencing of colorectal cancer patient: stool F194
SAMC3437835	16sRNA sequencing of colorectal cancer patient: stool F190
SAMC3437834	16sRNA sequencing of colorectal cancer patient: stool F187
SAMC3437833	16sRNA sequencing of colorectal cancer patient: stool F185
SAMC3437832	16sRNA sequencing of colorectal cancer patient: stool F184
SAMC3437831	16sRNA sequencing of colorectal cancer patient: stool F181
SAMC3437830	16sRNA sequencing of colorectal cancer patient: stool F178
SAMC3437829	16sRNA sequencing of colorectal cancer patient: stool F172
SAMC3437828	16sRNA sequencing of colorectal cancer patient: stool F171
SAMC3437827	16sRNA sequencing of colorectal cancer patient: stool F167
SAMC3437826	16sRNA sequencing of colorectal cancer patient: stool F162
SAMC3437825	16sRNA sequencing of colorectal cancer patient: stool F161
SAMC3437824	16sRNA sequencing of colorectal cancer patient: stool F160
SAMC3437823	16sRNA sequencing of colorectal cancer patient: stool F159
SAMC3437822	16sRNA sequencing of colorectal cancer patient: stool F152
SAMC3437821	16sRNA sequencing of colorectal cancer patient: stool F147
SAMC3437820	16sRNA sequencing of colorectal cancer patient: stool F146
SAMC3437819	16sRNA sequencing of colorectal cancer patient: stool F145
SAMC3437818	16sRNA sequencing of colorectal cancer patient: stool F142
SAMC3437817	16sRNA sequencing of colorectal cancer patient: stool F140
SAMC3437816	16sRNA sequencing of colorectal cancer patient: stool F138
SAMC3437815	16sRNA sequencing of colorectal cancer patient: stool F135
SAMC3437814	16sRNA sequencing of colorectal cancer patient: stool F134
SAMC3437813	16sRNA sequencing of colorectal cancer patient: stool F133
SAMC3437812	16sRNA sequencing of colorectal cancer patient: stool F132
SAMC3437811	16sRNA sequencing of colorectal cancer patient: stool F129
SAMC3437810	16sRNA sequencing of colorectal cancer patient: stool F126
SAMC3437809	16sRNA sequencing of colorectal cancer patient: stool F125
SAMC3437808	16sRNA sequencing of colorectal cancer patient: stool F124
SAMC3437807	16sRNA sequencing of colorectal cancer patient: stool F119
SAMC3437806	16sRNA sequencing of colorectal cancer patient: stool F112
SAMC3437805	16sRNA sequencing of colorectal cancer patient: stool F108
SAMC3437804	16sRNA sequencing of colorectal cancer patient: stool F106
SAMC3437803	16sRNA sequencing of colorectal cancer patient: stool F104
SAMC3437802	16sRNA sequencing of colorectal cancer patient: stool F102
SAMC3437801	16sRNA sequencing of colorectal cancer patient: stool F099
SAMC3437800	16sRNA sequencing of colorectal cancer patient: stool F098
SAMC3437799	16sRNA sequencing of colorectal cancer patient: stool F096
SAMC3437798	16sRNA sequencing of colorectal cancer patient: stool F089
SAMC3437797	16sRNA sequencing of colorectal cancer patient: stool F086
SAMC3437796	16sRNA sequencing of colorectal cancer patient: stool F082
SAMC3437795	16sRNA sequencing of colorectal cancer patient: stool F081
SAMC3437794	16sRNA sequencing of colorectal cancer patient: stool F080
SAMC3437793	16sRNA sequencing of colorectal cancer patient: stool F079
SAMC3437792	16sRNA sequencing of colorectal cancer patient: stool F078
SAMC3437791	16sRNA sequencing of colorectal cancer patient: stool F076
SAMC3437790	16sRNA sequencing of colorectal cancer patient: stool F074
SAMC3437789	16sRNA sequencing of colorectal cancer patient: stool F071
SAMC3437788	16sRNA sequencing of colorectal cancer patient: stool F070
SAMC3437787	16sRNA sequencing of colorectal cancer patient: stool F066
SAMC3437786	16sRNA sequencing of colorectal cancer patient: stool F063
SAMC3437785	16sRNA sequencing of colorectal cancer patient: stool F060
SAMC3437784	16sRNA sequencing of colorectal cancer patient: stool F058
SAMC3437783	16sRNA sequencing of colorectal cancer patient: stool F057
SAMC3437782	16sRNA sequencing of colorectal cancer patient: stool F055
SAMC3437781	16sRNA sequencing of colorectal cancer patient: stool F050
SAMC3437780	16sRNA sequencing of colorectal cancer patient: stool F049
SAMC3437779	16sRNA sequencing of colorectal cancer patient: stool F048
SAMC3437778	16sRNA sequencing of colorectal cancer patient: stool F047
SAMC3437777	16sRNA sequencing of colorectal cancer patient: stool F046