项目编号

PRJCA029964

项目标题

Unveiling potential microbial markers for metastatic colorectal cancer: Identification of gut and intratumoral microbiota and modelling for distant metastasis prediction

涉及领域

Environmental

数据类型

Whole genome sequencing

物种名称

human gut metagenome

描述信息

In this study, we conducted 16S rRNA gene sequencing of fecal samples obtained from CRC patients with and without distant metastasis, aiming to discern the gut microbiota associated with distant metastasis. Moreover, employing the BIC database, we sought to identify intratumoral microbiota linked to distant metastasis. Concurrently, our study delved into the correlation among gut and intratumoral microbiota associated with CRC distant metastasis, immune-related genes, immune infiltrating cells, and pertinent biological pathways. Last but not the least, leveraging the gut microbiota associated with distant metastasis of CRC, we constructed RF model demonstrating predictive significance. These findings held promise in furnishing novel insights pertinent to the diagnosis and therapeutic management of metastatic CRC.

样品范围

Environment

发布日期

2024-09-13

项目资金来源

机构	项目类型	授权项目ID
National Natural Science Foundation of China (NSFC)	General Program	2021GXNSFAA196008
Youth Science Foundation of Guangxi Medical University		GXMUYSF202402
Youth Research Project of Guangxi Medical University Affiliated Cancer Hospital		yuanqingji2023-10hao
Middle-aged and Young Teachers' Basic Ability Promotion Project of Guangxi (Basic Ability Promotion Project of Guangxi)		2021KY0087
China Postdoctoral Science Foundation		2023MD734155
Youth Science Foundation of Guangxi Medical University		GXMUYSF202357
uangxi Key Laboratory of Basic and Translational Research for Colorectal Cancer		-

提交者

Weizhong Tang (tangweizhong@gxmu.edu.cn)

提交单位

Guangxi Medical University Cancer Hospital

提交日期

2024-09-07

项目包含数据信息

资源名称	描述
BioSample (192) show	-
SAMC4126661	16sRNA sequencing of colorectal cancer patient: stoolS0239
SAMC4126660	16sRNA sequencing of colorectal cancer patient: stoolM0240
SAMC4126659	16sRNA sequencing of colorectal cancer patient: stoolF293
SAMC4126658	16sRNA sequencing of colorectal cancer patient: stoolF291
SAMC4126657	16sRNA sequencing of colorectal cancer patient: stoolF290
SAMC4126656	16sRNA sequencing of colorectal cancer patient: stoolF289
SAMC4126655	16sRNA sequencing of colorectal cancer patient: stoolF287
SAMC4126654	16sRNA sequencing of colorectal cancer patient: stoolF286
SAMC4126653	16sRNA sequencing of colorectal cancer patient: stoolF285
SAMC4126652	16sRNA sequencing of colorectal cancer patient: stoolF284
SAMC4126651	16sRNA sequencing of colorectal cancer patient: stoolF283
SAMC4126650	16sRNA sequencing of colorectal cancer patient: stoolF281
SAMC4126649	16sRNA sequencing of colorectal cancer patient: stoolF280
SAMC4126648	16sRNA sequencing of colorectal cancer patient: stoolF277
SAMC4126647	16sRNA sequencing of colorectal cancer patient: stoolF276
SAMC4126646	16sRNA sequencing of colorectal cancer patient: stoolF275
SAMC4126645	16sRNA sequencing of colorectal cancer patient: stoolF273
SAMC4126644	16sRNA sequencing of colorectal cancer patient: stoolF272
SAMC4126643	16sRNA sequencing of colorectal cancer patient: stoolF271
SAMC4126642	16sRNA sequencing of colorectal cancer patient: stoolF270
SAMC4126641	16sRNA sequencing of colorectal cancer patient: stoolF269
SAMC4126640	16sRNA sequencing of colorectal cancer patient: stoolF268
SAMC4126639	16sRNA sequencing of colorectal cancer patient: stoolF265
SAMC4126638	16sRNA sequencing of colorectal cancer patient: stoolF262
SAMC4126637	16sRNA sequencing of colorectal cancer patient: stoolF261
SAMC4126636	16sRNA sequencing of colorectal cancer patient: stoolF260
SAMC4126635	16sRNA sequencing of colorectal cancer patient: stoolF259
SAMC4126634	16sRNA sequencing of colorectal cancer patient: stoolF256
SAMC4126633	16sRNA sequencing of colorectal cancer patient: stoolF255
SAMC4126632	16sRNA sequencing of colorectal cancer patient: stoolF254
SAMC4126631	16sRNA sequencing of colorectal cancer patient: stoolF253
SAMC4126630	16sRNA sequencing of colorectal cancer patient: stoolF250
SAMC4126629	16sRNA sequencing of colorectal cancer patient: stoolF249
SAMC4126628	16sRNA sequencing of colorectal cancer patient: stoolF248
SAMC4126627	16sRNA sequencing of colorectal cancer patient: stoolF247
SAMC4126626	16sRNA sequencing of colorectal cancer patient: stoolF246
SAMC4126625	16sRNA sequencing of colorectal cancer patient: stoolF245
SAMC4126624	16sRNA sequencing of colorectal cancer patient: stoolF244
SAMC4126623	16sRNA sequencing of colorectal cancer patient: stoolF243
SAMC4126622	16sRNA sequencing of colorectal cancer patient: stoolF242
SAMC4126621	16sRNA sequencing of colorectal cancer patient: stoolF240
SAMC4126620	16sRNA sequencing of colorectal cancer patient: stoolF237
SAMC4126619	16sRNA sequencing of colorectal cancer patient: stoolF234
SAMC4126618	16sRNA sequencing of colorectal cancer patient: stoolF233
SAMC4126617	16sRNA sequencing of colorectal cancer patient: stoolF232
SAMC4126616	16sRNA sequencing of colorectal cancer patient: stoolF231
SAMC4126615	16sRNA sequencing of colorectal cancer patient: stoolF230
SAMC4126614	16sRNA sequencing of colorectal cancer patient: stoolF228
SAMC4126613	16sRNA sequencing of colorectal cancer patient: stoolF227
SAMC4126612	16sRNA sequencing of colorectal cancer patient: stoolF224
SAMC4126611	16sRNA sequencing of colorectal cancer patient: stoolF223
SAMC4126610	16sRNA sequencing of colorectal cancer patient: stoolF221
SAMC4126609	16sRNA sequencing of colorectal cancer patient: stoolF220
SAMC4126608	16sRNA sequencing of colorectal cancer patient: stoolF219
SAMC4126607	16sRNA sequencing of colorectal cancer patient: stoolF217
SAMC4126606	16sRNA sequencing of colorectal cancer patient: stoolF216
SAMC4126605	16sRNA sequencing of colorectal cancer patient: stoolF215
SAMC4126604	16sRNA sequencing of colorectal cancer patient: stoolF214
SAMC4126603	16sRNA sequencing of colorectal cancer patient: stoolF213
SAMC4126602	16sRNA sequencing of colorectal cancer patient: stoolF212
SAMC4126601	16sRNA sequencing of colorectal cancer patient: stoolF211
SAMC4126600	16sRNA sequencing of colorectal cancer patient: stoolF210
SAMC4126599	16sRNA sequencing of colorectal cancer patient: stoolF208
SAMC4126598	16sRNA sequencing of colorectal cancer patient: stoolF207
SAMC4126597	16sRNA sequencing of colorectal cancer patient: stoolF206
SAMC4126596	16sRNA sequencing of colorectal cancer patient: stoolF205
SAMC4126595	16sRNA sequencing of colorectal cancer patient: stoolF204
SAMC4126594	16sRNA sequencing of colorectal cancer patient: stoolF203
SAMC4126593	16sRNA sequencing of colorectal cancer patient: stoolF202
SAMC4126592	16sRNA sequencing of colorectal cancer patient: stoolF200
SAMC4126591	16sRNA sequencing of colorectal cancer patient: stoolF199
SAMC4126590	16sRNA sequencing of colorectal cancer patient: stoolF198
SAMC4126589	16sRNA sequencing of colorectal cancer patient: stoolF197
SAMC4126588	16sRNA sequencing of colorectal cancer patient: stoolF196
SAMC4126587	16sRNA sequencing of colorectal cancer patient: stoolF194
SAMC4126586	16sRNA sequencing of colorectal cancer patient: stoolF191
SAMC4126585	16sRNA sequencing of colorectal cancer patient: stoolF190
SAMC4126584	16sRNA sequencing of colorectal cancer patient: stoolF188
SAMC4126583	16sRNA sequencing of colorectal cancer patient: stoolF187
SAMC4126582	16sRNA sequencing of colorectal cancer patient: stoolF186
SAMC4126581	16sRNA sequencing of colorectal cancer patient: stoolF185
SAMC4126580	16sRNA sequencing of colorectal cancer patient: stoolF184
SAMC4126579	16sRNA sequencing of colorectal cancer patient: stoolF183
SAMC4126578	16sRNA sequencing of colorectal cancer patient: stoolF182
SAMC4126577	16sRNA sequencing of colorectal cancer patient: stoolF181
SAMC4126576	16sRNA sequencing of colorectal cancer patient: stoolF179
SAMC4126575	16sRNA sequencing of colorectal cancer patient: stoolF178
SAMC4126574	16sRNA sequencing of colorectal cancer patient: stoolF177
SAMC4126573	16sRNA sequencing of colorectal cancer patient: stoolF176
SAMC4126572	16sRNA sequencing of colorectal cancer patient: stoolF174
SAMC4126571	16sRNA sequencing of colorectal cancer patient: stoolF172
SAMC4126570	16sRNA sequencing of colorectal cancer patient: stoolF171
SAMC4126569	16sRNA sequencing of colorectal cancer patient: stoolF170
SAMC4126568	16sRNA sequencing of colorectal cancer patient: stoolF168
SAMC4126567	16sRNA sequencing of colorectal cancer patient: stoolF167
SAMC4126566	16sRNA sequencing of colorectal cancer patient: stoolF165
SAMC4126565	16sRNA sequencing of colorectal cancer patient: stoolF164
SAMC4126564	16sRNA sequencing of colorectal cancer patient: stoolF162
SAMC4126563	16sRNA sequencing of colorectal cancer patient: stoolF161
SAMC4126562	16sRNA sequencing of colorectal cancer patient: stoolF160
SAMC4126561	16sRNA sequencing of colorectal cancer patient: stoolF159
SAMC4126560	16sRNA sequencing of colorectal cancer patient: stoolF158
SAMC4126559	16sRNA sequencing of colorectal cancer patient: stoolF157
SAMC4126558	16sRNA sequencing of colorectal cancer patient: stoolF156
SAMC4126557	16sRNA sequencing of colorectal cancer patient: stoolF154
SAMC4126556	16sRNA sequencing of colorectal cancer patient: stoolF153
SAMC4126555	16sRNA sequencing of colorectal cancer patient: stoolF152
SAMC4126554	16sRNA sequencing of colorectal cancer patient: stoolF150
SAMC4126553	16sRNA sequencing of colorectal cancer patient: stoolF148
SAMC4126552	16sRNA sequencing of colorectal cancer patient: stoolF147
SAMC4126551	16sRNA sequencing of colorectal cancer patient: stoolF146
SAMC4126550	16sRNA sequencing of colorectal cancer patient: stoolF145
SAMC4126549	16sRNA sequencing of colorectal cancer patient: stoolF142
SAMC4126548	16sRNA sequencing of colorectal cancer patient: stoolF140
SAMC4126547	16sRNA sequencing of colorectal cancer patient: stoolF138
SAMC4126546	16sRNA sequencing of colorectal cancer patient: stoolF136
SAMC4126545	16sRNA sequencing of colorectal cancer patient: stoolF135
SAMC4126544	16sRNA sequencing of colorectal cancer patient: stoolF134
SAMC4126543	16sRNA sequencing of colorectal cancer patient: stoolF133
SAMC4126542	16sRNA sequencing of colorectal cancer patient: stoolF132
SAMC4126541	16sRNA sequencing of colorectal cancer patient: stoolF131
SAMC4126540	16sRNA sequencing of colorectal cancer patient: stoolF130
SAMC4126539	16sRNA sequencing of colorectal cancer patient: stoolF129
SAMC4126538	16sRNA sequencing of colorectal cancer patient: stoolF126
SAMC4126537	16sRNA sequencing of colorectal cancer patient: stoolF125
SAMC4126536	16sRNA sequencing of colorectal cancer patient: stoolF122
SAMC4126535	16sRNA sequencing of colorectal cancer patient: stoolF121
SAMC4126534	16sRNA sequencing of colorectal cancer patient: stoolF120
SAMC4126533	16sRNA sequencing of colorectal cancer patient: stoolF119
SAMC4126532	16sRNA sequencing of colorectal cancer patient: stoolF118
SAMC4126531	16sRNA sequencing of colorectal cancer patient: stoolF116
SAMC4126530	16sRNA sequencing of colorectal cancer patient: stoolF115
SAMC4126529	16sRNA sequencing of colorectal cancer patient: stoolF114
SAMC4126528	16sRNA sequencing of colorectal cancer patient: stoolF113
SAMC4126527	16sRNA sequencing of colorectal cancer patient: stoolF112
SAMC4126526	16sRNA sequencing of colorectal cancer patient: stoolF111
SAMC4126525	16sRNA sequencing of colorectal cancer patient: stoolF110
SAMC4126524	16sRNA sequencing of colorectal cancer patient: stoolF109
SAMC4126523	16sRNA sequencing of colorectal cancer patient: stoolF108
SAMC4126522	16sRNA sequencing of colorectal cancer patient: stoolF107
SAMC4126521	16sRNA sequencing of colorectal cancer patient: stoolF106
SAMC4126520	16sRNA sequencing of colorectal cancer patient: stoolF105
SAMC4126519	16sRNA sequencing of colorectal cancer patient: stoolF104
SAMC4126518	16sRNA sequencing of colorectal cancer patient: stoolF102
SAMC4126517	16sRNA sequencing of colorectal cancer patient: stoolF100
SAMC4126516	16sRNA sequencing of colorectal cancer patient: stoolF099
SAMC4126515	16sRNA sequencing of colorectal cancer patient: stoolF098
SAMC4126514	16sRNA sequencing of colorectal cancer patient: stoolF097
SAMC4126513	16sRNA sequencing of colorectal cancer patient: stoolF096
SAMC4126512	16sRNA sequencing of colorectal cancer patient: stoolF095
SAMC4126511	16sRNA sequencing of colorectal cancer patient: stoolF094
SAMC4126510	16sRNA sequencing of colorectal cancer patient: stoolF093
SAMC4126509	16sRNA sequencing of colorectal cancer patient: stoolF091
SAMC4126508	16sRNA sequencing of colorectal cancer patient: stoolF089
SAMC4126507	16sRNA sequencing of colorectal cancer patient: stoolF086
SAMC4126506	16sRNA sequencing of colorectal cancer patient: stoolF085
SAMC4126505	16sRNA sequencing of colorectal cancer patient: stoolF084
SAMC4126504	16sRNA sequencing of colorectal cancer patient: stoolF083
SAMC4126503	16sRNA sequencing of colorectal cancer patient: stoolF082
SAMC4126502	16sRNA sequencing of colorectal cancer patient: stoolF081
SAMC4126501	16sRNA sequencing of colorectal cancer patient: stoolF080
SAMC4126500	16sRNA sequencing of colorectal cancer patient: stoolF079
SAMC4126499	16sRNA sequencing of colorectal cancer patient: stoolF078
SAMC4126498	16sRNA sequencing of colorectal cancer patient: stoolF077
SAMC4126497	16sRNA sequencing of colorectal cancer patient: stoolF076
SAMC4126496	16sRNA sequencing of colorectal cancer patient: stoolF075
SAMC4126495	16sRNA sequencing of colorectal cancer patient: stoolF074
SAMC4126494	16sRNA sequencing of colorectal cancer patient: stoolF073
SAMC4126493	16sRNA sequencing of colorectal cancer patient: stoolF072
SAMC4126492	16sRNA sequencing of colorectal cancer patient: stoolF071
SAMC4126491	16sRNA sequencing of colorectal cancer patient: stoolF070
SAMC4126490	16sRNA sequencing of colorectal cancer patient: stoolF069
SAMC4126489	16sRNA sequencing of colorectal cancer patient: stoolF068
SAMC4126488	16sRNA sequencing of colorectal cancer patient: stoolF067
SAMC4126487	16sRNA sequencing of colorectal cancer patient: stoolF066
SAMC4126486	16sRNA sequencing of colorectal cancer patient: stoolF063
SAMC4126485	16sRNA sequencing of colorectal cancer patient: stoolF062
SAMC4126484	16sRNA sequencing of colorectal cancer patient: stoolF061
SAMC4126483	16sRNA sequencing of colorectal cancer patient: stoolF060
SAMC4126482	16sRNA sequencing of colorectal cancer patient: stoolF059
SAMC4126481	16sRNA sequencing of colorectal cancer patient: stoolF058
SAMC4126480	16sRNA sequencing of colorectal cancer patient: stoolF057
SAMC4126479	16sRNA sequencing of colorectal cancer patient: stoolF056
SAMC4126478	16sRNA sequencing of colorectal cancer patient: stoolF055
SAMC4126477	16sRNA sequencing of colorectal cancer patient: stoolF053
SAMC4126476	16sRNA sequencing of colorectal cancer patient: stoolF052
SAMC4126475	16sRNA sequencing of colorectal cancer patient: stoolF051
SAMC4126474	16sRNA sequencing of colorectal cancer patient: stoolF050
SAMC4126473	16sRNA sequencing of colorectal cancer patient: stoolF049
SAMC4126472	16sRNA sequencing of colorectal cancer patient: stoolF048
SAMC4126471	16sRNA sequencing of colorectal cancer patient: stoolF047
SAMC4126470	16sRNA sequencing of colorectal cancer patient: stoolF046