| HRA000400
(Controlled Access)
|
A comprehensive transcriptome survey of pig, provides information essential for a complete understanding of the mechanisms of tissue specialization that underlies economic traits in pig and accelerate the use of pig as a biomedical model. We enhanced the definition of four distinct transcripts and characterize the features and variability with respect to the known physiology of tissues. We demonstrated the extraordinary diversity among 47 anatomically distinct skeletal muscles and six adipose depots, which link to their diverse origins, metabolic features, heterogeneous composition. We also jointly analysed the long-range regulation of promoters by their enhancers with downstream transcription in subcutaneous adiposes for six mammals, and illuminated the evolutionary stability of transcription is mainly contribute to the multiple enhancers serve to buffer transcriptional patterns for a target protein coding gene against genetic perturbations, thereby conferring robustness during speciation. |
