| Accession | SAMC1879944 |
|---|---|
| Accession in Other Database | GSA-Human: HRS271428 |
| Sample name | 3691_lncRNA |
| Title | glioma stem cell |
| Sample type | Human sample |
| Organism | Homo sapiens |
| Description | glioma stem cell |
| Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA001176 in the GSA-Human system. |
| Release date | 2021-09-08 |
| BioProject Accession | PRJCA005969 |
| Submitter | Nu Zhang (zhangnu2@mail.sysu.edu.cn) |
| Organization | Sun Yat-sen University |
| Submission date | 2023-06-18 |
| Resource name | Description |
|---|---|
| GSA-Human (1) | - |
| HRA001176 (Controlled Access) | Aberrant EGFR activation is observed in over 50% of cases of adult glioblastoma (GBM). Nevertheless, EGFR antibodies are ineffective in clinical GBM treatment, suggesting the existence of redundant EGFR activation mechanisms. Whether circular RNA (circRNA) encodes a protein involved in EGFR-driven GBM remains unclear. We reported an unexpected mechanism in which circular EGFR RNA (circ-EGFR) encodes a novel EGFR variant to sustained EGFR activation.These were the rRNA depeleted sequencing data for mRNA and lncRNA detecttion. |