Accession SAMC1892813
Accession in Other Database GSA-Human: HRS276190
Sample name P13-T1
Title multiple primary lung adenocarcinomas
Sample type Human sample
Organism Homo sapiens
Description Actionable gene mutation analysis of surgery tissue samples was determined by capture single molecule amplification and resequencing technology (capSMART) for a targeted NGS panel assay of 10 NSCLC-related driver genes.
Attributes *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA001237 in the GSA-Human system.
Release date 2021-08-31
BioProject Accession PRJCA006357
Submitter pingping  song  (spp128@126.com)
Organization Tumor Hospital affiliated to Shandong First Medical University
Submission date 2023-06-18

Sample Data

Resource name Description
GSA-Human (1) -
HRA001237  (Controlled Access) Multiple primary lung cancers (MPLCs) are an increasingly well-known clinical phenomenon, but there is a lack of high-level evidence for their optimal clinical diagnosis and therapeutic approaches. Thus, we analysed genetic variation to determine the intertumoural heterogeneity and branch evolution of synchronous multiple primary lung adenocarcinomas. We performed multiplex mutational sequencing on 93 synchronous multiple primary lung adenocarcinoma lesions from 42 patients who underwent surgical resection. Remarkable intertumoural heterogeneity and frequent branch mutations were found in synchronous multiple primary lung adenocarcinomas.
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