Accession | SAMC2192634 |
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Accession in Other Database | GSA-Human: HRS431330 |
Sample name | Sample 6 |
Title | Sample 6 |
Sample type | Human sample |
Organism | Homo sapiens |
Description | cord blood CD34+ ex-vivo cultured for 4 days |
Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA002780 in the GSA-Human system. |
Release date | 2024-07-13 |
BioProject Accession | PRJCA010096 |
Submitter | Bin Guo (jybinguo@shsmu.edu.cn) |
Organization | Shanghai Jiao Tong University |
Submission date | 2023-06-18 |
Resource name | Description |
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GSA-Human (1) | - |
HRA002780 (Controlled Access) | RNA-seq analysis was performed to compare differentially expressed genes in freshly isolated and ex-vivo cultured human cord blood CD34+ cells. Mitochondrion related genes are upregulated in CD34+ hematopoietic stem and progenitor cells upon ex vivo culture. In vivo transplantation experiments demonstrate that stemness of CD34+ cells is significantly decreased due to oxidative stress induced by ex vivo culture. |