| Accession | SAMC2192641 |
|---|---|
| Accession in Other Database | GSA-Human: HRS431332 |
| Sample name | Sample 8 |
| Title | Sample 8 |
| Sample type | Human sample |
| Organism | Homo sapiens |
| Description | cord blood CD34+ ex-vivo cultured for 4 days |
| Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA002780 in the GSA-Human system. |
| Release date | 2024-07-13 |
| BioProject Accession | PRJCA010096 |
| Submitter | Bin Guo (jybinguo@shsmu.edu.cn) |
| Organization | Shanghai Jiao Tong University |
| Submission date | 2023-06-18 |
| Resource name | Description |
|---|---|
| GSA-Human (1) | - |
| HRA002780 (Controlled Access) | RNA-seq analysis was performed to compare differentially expressed genes in freshly isolated and ex-vivo cultured human cord blood CD34+ cells. Mitochondrion related genes are upregulated in CD34+ hematopoietic stem and progenitor cells upon ex vivo culture. In vivo transplantation experiments demonstrate that stemness of CD34+ cells is significantly decreased due to oxidative stress induced by ex vivo culture. |