Accession SAMC2324583
Accession in Other Database GSA-Human: HRS470177
Sample name Aged_MSC3
Title Aged3
Sample type Human sample
Organism Homo sapiens
Description single cell trascriptome from MSCs of healthy donor
Attributes
Isolate not collected
Age
Biomaterial provider Institute of Hematology and Blood Diseases Hospital, Tianjin, China
Sex male
Tissue Bone marrow
Disease
Cell line
Cell subtype
Cell type
Culture collection
Development stage
Disease stage
Ethnicity Han Chinese
Health State
Karyotype
Phenotype
Population
Race
Type
Treatment
Collection date 2022-09-01
Custom attributes
Release date 2024-10-12
BioProject Accession PRJCA012439
Submitter Yuchen  Gao  (zhanglei1@ihcams.ac.cn)
Organization Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences
Submission date 2023-06-18

Sample Data

Resource name Description
GSA-Human (1) -
HRA003258  (Open Access) In this study, we investigated the characteristics of bone marrow MSC derived from young and aged donors by single-cell transcriptomic analysis. As compared to BM-MSCs derived from young donors, aged MSCs showed higher degree of senescence and impaired immunosuppressive function. Moreover, we further explored the molecular mechanisms underpin the downregulation of immunosuppressive function.
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Samples (0)