| Accession | SAMC2491483 |
|---|---|
| Accession in Other Database | GSA-Human: HRS510708 |
| Sample name | BC70posD |
| Title | WES |
| Sample type | Human sample |
| Organism | Homo sapiens |
| Description | WES |
| Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA003759 in the GSA-Human system. |
| Release date | 2023-12-30 |
| BioProject Accession | PRJCA013875 |
| Submitter | Zhigang Yu (yzg@medmail.com.cn) |
| Organization | The Second Hospital of Shandong University |
| Submission date | 2023-06-18 |
| Resource name | Description |
|---|---|
| GSA-Human (1) | - |
| HRA003759 (Controlled Access) | We performed whole-exome and RNA sequencing (RNAseq) analysis on 233 clinical samples (including matched pre- and posttreatment tumors) from 50 BC patients with rigorously definite response to NAC. This study revealed an improved understanding of genomic and transcriptomic landscape related to NAC in BC, identified novel biomarkers underlying NAC resistance and provided therapeutics opportunity beyond current neoadjuvant regimens. |