样本编号 SAMC2926304
外部数据库编号 GSA-Human: HRS894910
样品名称 NFH_sample59
样本标题 Transcriptomic sequencing of newly diagnosed B-ALL patients
样品类型 Human sample
物种名称 Homo sapiens
描述信息 Transcriptomic sequencing of newly diagnosed B-ALL patients
样本属性
分离株名称 not collected
年龄
实验材料提供者 Nanfang Hospital
性别 male
组织器官 Bone marrow
疾病名称
细胞系
细胞亚型
细胞类型
收集/保存方法
发育阶段
疾病分期
血统性(民族)
健康状况
核型
表型
人口
种族(人种)
类型
处理方法
用户自定义属性
发布日期 2023-07-18
项目编号 PRJCA018245
提交者 Hongsheng  Zhou  (zhs1@i.smu.edu.cn)
提交单位 Nanfang Hospital
提交日期 2023-07-19

样本包含数据信息

资源名称 描述
GSA-Human (1) -
HRA005077  (Open Access) Metabolic reprogramming is a hallmark and therapeutic target in cancer, as cancer cells accumulate metabolic changes to meet biosynthetic and energy demands, sustaining rapid proliferation while generating metabolic heterogeneity. Heterogeneous metabolic preferences and dependencies exist among different cancer types and even within cancer cells of the same tissue. Cancer cells acquire metabolic adaptability by responding to various endogenous and exogenous signals, some of which promote malignant cell growth and render them vulnerable to inhibition by key pathway inhibitors. To explore the metabolic features of acute B-cell lymphoblastic leukemia (B-ALL), we collected bone marrow samples from newly diagnosed patients in the PDT-ALL-2016 cohort at Southern Hospital from 2016-2020 for transcriptome sequencing (n=91) and untargeted metabolomics profiling (n=69), in addition to conducting transcriptome sequencing on two B-ALL cell lines (BALL-1 and HAL-01).
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