| Accession | SAMC3135534 |
|---|---|
| Accession in Other Database | GSA-Human: HRS979965 |
| Sample name | Case7 |
| Title | ACA7 |
| Sample type | Human sample |
| Organism | Homo sapiens |
| Description | Single-cell Sequencing Reveals Intra-tumoral Heterogeneity and Malignant Progression of Adrenal Incidentaloma |
| Attributes | *This sample record contains additional controlled-access information that is avaiable from GSA-Human by requesting study HRA005846 in the GSA-Human system. |
| Release date | 2025-09-16 |
| BioProject Accession | PRJCA020570 |
| Submitter | Meng Wang (wm19921276529@163.com) |
| Organization | Shanghai Jiao Tong University School of Medicine |
| Submission date | 2023-10-28 |
| Resource name | Description |
|---|---|
| GSA-Human (1) | - |
| HRA005846 (Controlled Access) | Adrenal incidentaloma, the most prevalent type of adrenal tumors, exhibits marked heterogeneity, giving rise to divergent clinical outcomes. This study aims to elucidate the heterogeneous tumor progression characteristics of adrenocortical and medullary adenomas. To achieve this, we employed single-cell RNA sequencing (scRNA-seq) to construct a comprehensive transcriptomic atlas comprising 49,057 individual cells obtained from 12 donors. The dataset encompassed various subtypes, including cortisol-producing adrenocortical adenomas (CPA), aldosterone-producing adenomas (APA), pheochromocytomas (PCC), and paragangliomas. |