| HRA007091
(Controlled Access)
|
Primary graft dysfunction (PGD) is the leading cause of early morbidity and mortality after lung transplantation. Neutrophils play a critical role in the exacerbated inflammatory process of severe PGD caused by lung ischemia-reperfusion injury (IRI). Nevertheless, the comprehensive elucidation of neutrophil phenotypic heterogeneity remains predominantly unexplored. We performed bulk RNA-Seq of neutrophils from the paired blood samples before and after transplantation. |