Endothelial cell

Cell Taxonomy ID: CT:00000153
Cell Ontology ID: CL:0000115
Synonyms: Endotheliocyte
Author: Dee Lauzon, Sue Lancelle, Marian Rice
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  • Endothelial cell is associated with 1492 cell markers in 56 conditions and 80 tissues across 7 species, supported by 280 publications.
  • 263 cell markers are predicted to be cell surface marker(s) which code for membrane-bound protein products, in which 250 are supported by evidence at protein level and 241 are annotated with well-characterized antibodies.
  • Based on reported cell markers, the similarity score between Endothelial cell and Smooth muscle cell is 0.16.
  • Endothelial cell is distributed in 13 tissues in Tabula Sapiens (human) and 10 tissues in Tabula Muris (mouse).
  • For Endothelial cell, there are 405 conserved cell markers whose orthologs are also reported as cell markers for this cell type.
  • The relevant cell markers of Endothelial cell are ranked in terms of supported literature, expression enrichment and conservation.
  • Show value
No. of publications0306090120PECAM1VWFCD34VECADKDRCLDN5CD105FLT1MCAMRAMP2GNG11PTPRCFLT4LYVE1ERGTEKPLVAPTM4SF1EMCNELEECSCRTHBDTIE1VCAM1LDB2CLEC14AA2MELK3FABP4ADGRF5********************************************Endothelial cell: top publication-supported markers of Homo sapiens
ADGRF5FABP4ELK3A2MCLEC14ALDB2VCAM1TIE1THBDECSCRELEEMCNTM4SF1PLVAPTEKERGLYVE1FLT4PTPRCGNG11RAMP2MCAMFLT1CD105CLDN5KDRVECADCD34VWFPECAM1Adipose tissueAnterior hippocampusAorta-gonad-mesonephroBloodBlood plasmaBlood vesselBone marrowBone tissueBrainBreastCarotid artery segmentCerebral cortexChorionic villusColonCorneaCorpus luteumDental pulpDermisEmbryoEntorhinal cortexEsophagusEyeFemoral arteryGonadHead and neckHeartIntervertebral diskKidneyKidney (organoid)LiverLungLymph nodeLymphatic vesselMedian basilic veinMuscle organOmentumOral cavityOvaryPancreasPeritoneumPosterior hippocampusPrefrontal cortexRectus femorisRenal glomerulusSkeletal muscle organSkin of bodyStomachSubcutaneous adipose tissueTemporal lobeTestisThyroid glandUrinary bladderUveaWhite adipose tissue1513129855554444333333333322222222222222222222222222222222111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111111015Number of publications in support of cell markers for Endothelial cell in Homo sapiens
SpeciesTissueTissue IDConditionDisease IDCell markerSourcePMID
Homo sapiensLiverUBERON:0002107Lung non-small cell carcinomaDOID:3908VECADCell Taxonomy33106178
Homo sapiensSkin of bodyUBERON:0002097MelanomaDOID:1909VECADCellMatch27124452
Homo sapiensLungUBERON:0002048Lung cancerDOID:1324VECADCell Taxonomy30979687
Homo sapiensLungUBERON:0002048Lung non-small cell carcinomaDOID:3908VECADCellMatch29988129
Homo sapiensLungUBERON:0002048Hepatocellular carcinomaDOID:684VECADCell Taxonomy33357445
Showing 1 to 5 of 2,806 entries
Show publication-supported cell markers
Show publication-supported cell markers or rank cell markers by the y-axis value
Rank by highly expressed ratio
RatioNumber of samples00.20.40.60.81020406080100TIE1ADGRL4ERGPECAM1GNG11CLDN5ECSCRVECADKDRESAMCD105TM4SF1EMCNFLT1VWFTHBDRAMP2PLVAPTEKCD34LDB2TSPAN7APOLD1MCAMELEFLT4LYVE1VCAM1PROM1CD45.RAHighly expressed samples (HE, FDR less than 0.05)Total samples (E)Highly expressed ratio (HE/E)Highly expressed ratio of cell markers
log2FC-202468CLDN5PLVAPGNG11RAMP2VWFTM4SF1FLT1ESAMECSCRPECAM1CD105ADGRL4EMCNVECADELETSPAN7CD34KDRLDB2LYVE1THBDTIE1ERGAPOLD1TEKFLT4MCAMVCAM1PROM1CD45.RACell marker differential expression pattern (FDR less than 0.05) in Endothelial cell across samples
Specificity score00.20.40.60.81ELEADGRL4EMCNECSCRTEKVWFVECADFLT4KDRCLDN5ERGRAMP2FLT1MCAMESAMPLVAPTIE1THBDPECAM1LYVE1TM4SF1CD34GNG11CD105VCAM1APOLD1TSPAN7LDB2PROM1CD45.RACell marker expression specificity in Endothelial cell across samples
  • For Endothelial cell, the similarity of reported cell marker composition between different species is shown below.
  • The conserved cell markers and their orthologous genes which are also reported as cell markers for the same cell type are showed below.
Endothelial cell (non-professional APC)Stromal cellEndothelial cell (APC)Smooth muscle cellFibroblastGonadal endothelial cellMesenchymal stem cellEndothelial cell (endothelial to mesenchymal transMacrophageEpithelial cellChondrocyteBasal cellMesothelial cellStratified epithelial cellAstrocyteNeuronMonocyteT cellMicroglial cellProfessional antigen presenting cellDendritic cellEndothelial cell of hepatic sinusoidStem cellErythroid progenitor cellMast cellGoblet cellB cellMitotic fetal germ cellMyeloid cellNeutrophilEndothelial cell: similarity score of Homo sapiens
SpeciesTissueCell type in comparison Marker similarity score
The similarity score (0-1) is calculated between two cell types by the number of common markers normalized by union of marker set sizes. One represents the same marker sets of two cell types and zero means the two cell types share no common markers.
AllChorionic villusHematopoietic stem cell1
AllSubcutaneous adipose tissuePericyte0.67
AllSkeletal muscle organAdventitial cell0.6
AllAdipose tissuePericyte0.55
AllVisual cortexSmooth muscle cell0.5
Showing 1 to 5 of 2,110 entries
Percentage (%)051015202530EyeFatKidneyLiverLymph nodePancreasProstateSalivary glandSkin of bodySpleenTracheaUterusVasculatureTissue distribution of Endothelial cell in Homo sapiens (Tabula Sapiens)
Set the filters of cell number, ROGUE, silhouette coefficient, and their averaged estimates by adjusting the hover cursors of the legends.
Cell numberScoreSample1101001,00010,000100,0001,000,000-0.6-0.300.30.60.91.2Cell numberROGUEAverage ROGUESilhouette coefficientAverage silhouette coefficientQuality evaluation of cell clusters in samples