circAtlas 3.0 a gateway to 3 million standardized named vertebrate circular RNAs

Welcome to circAtlas 3.0   

Circular RNAs (circRNAs) are a novel class of RNAs with important biological implications. Currently, a large number of circRNAs have been identified from high-throughput RNA-seq datasets. However, functional annotation and prioritization of these circRNAs for further experimental validation and functional investigation is the bottleneck step for current circRNA studies.
Now, we have updated circAltas 2.0 to circAtlas 3.0 (current version) , which integrates more than over 3.1 million circRNAs across 10 species (human, macaque, mouse, rat, pig, chicken, dog, sheep, cat, rabbit) and a variety of tissues. The circAtlas 3.0 can fill this gap by integrating the most comprehensive circRNAs and their expression and functional profiles in vertebrates, providing a foundation for circRNA studies and serving as a powerful starting point for investigating their biological significance.

News and Events:
2023.06    circAltas 3.0 Released(Release History)...
2023.05    New address:https://ngdc.cncb.ac.cn/circatlas.
Publications:
CircAtlas: an integrated resource of one million highly accurate circular RNAs from 1070 vertebrate transcriptomes.  Genome Biology. 2020; 21: 101.

Dataset Summary

10

SPECIES

3,179,560

CIRCRNAS

33

TISSUES

2,609/65

SAMPLES (Illumina/nanopore)
Homo
sapiens
768,986
Macaca
mulatta
521,794
Mus
musculus
287,653
Rattus
norvegicus
121,825
Oryctolagu
cuniculus
121,216
Canis lupus
familiaris
358,659
Felis
catus
161,566
Sus
scrofa
424,653
Ovis
aries
114,144
Gallus
gallus
124,205

Explore circAltas

Browse
By Species
Browse and search circRNAs by species.
By Tissue
Browse and search circRNAs by tissue.

By ID
Browse and search circRNAs by circRNA ID(host gene, position, unform ID, circAltas ID and other database ID).
Orthologous
Conserved circRNAs
Cross-species circRNA conservation information.
Converter
Convert ID
Convert IDs from different circRNA databases and assemblies.
Expression
Normal tissues
Expression of circRNAs in normal tissues.
Cancer tisssues
Expression of circRNAs in various cancers by Mioncocirc and CSCD2.

Single cells
Expression of circRNAs in various cell types.
Sequences
Full-length
Full-length of circRNAs predicted by Nanopore, CIRI-full and exons.
Isoforms
circRNA isoforms from long-read sequencing.

RNA structures
Prediction of the second RNA structure of circRNAs.
Translations
ORFs
Predict potential open reading frames on circRNAs.
IRES
Prediction of the internal ribosomal entry sites on circRNAs.
Functions
RBP Binding
Prediction of the RBP binding sites on circRNAs.
miRNA Binding
Providing predicted miRNA binding sites of the circRNA.

Network annotation
Annotate circRNA functions using gene co-expression, miRNA and RBP binding networks.