Dataset

Data release 1.0

CVD Atlas ID	CVDS000015
Data type	GWAS summary statistics
Disease/trait	Low density lipoprotein cholesterol measurement
Title	Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation.
PubMed ID	35213538
GWAS Catalog link	GCST90092887

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Gene	Tissue	#SNPs	PP.H4.abf	PP4/PP3	Coloc SNP	GWAS risk SNP	PP.H0.abf	PP.H1.abf	PP.H2.abf	PP.H3.abf
CDKN2B	Muscle_Skeletal	53	0.98	78.3	rs10811652	rs10757277	9.21e-4	3.24e-3	3.84e-3	1.25e-2
CDKN2B-AS1	Cells_Cultured_fibroblasts	23	0.91	92.0	rs7857345	rs10757277	1.09e-2	1.83e-3	6.45e-2	9.92e-3
DHX33	Muscle_Skeletal	129	0.92	44.2	rs8066805	rs766542348	1.51e-13	5.52e-14	5.92e-2	2.08e-2
LRP10	Whole_Blood	25	0.93	93.3	rs66535205	rs577666081	3.92e-3	7.26e-4	5.86e-2	9.94e-3
MIS12	Whole_Blood	101	0.92	43.8	rs8066805	rs766542348	6.96e-10	2.57e-10	5.93e-2	2.10e-2
MIS12	Brain_Frontal_Cortex_BA9	83	0.88	34.1	rs8069315	rs766542348	1.04e-2	3.66e-3	7.59e-2	2.59e-2
MTAP	Adipose_Visceral_Omentum	403	0.93	42.6	rs10965153	rs10757277	4.60e-22	2.09e-22	5.01e-2	2.18e-2
WDR41	Heart_Atrial_Appendage	279	0.92	188	rs6453319	rs529899846	2.27e-11	1.66e-12	7.92e-2	4.87e-3

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