Disease

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Disease	Hypertension
CVD Atlas ID	CVDD000029
MeSH ID	D006973
Ontology ID	NCIT:C3117
Description [MeSH]	Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Gene	Score

Search:

Dataset	Reported disease	Tissue/cell type	Omics	Data accession
CVDS000018	Atrial fibrillation	Epicardial adipose tissue	Transcriptomics	GSE135445
CVDS000066	Atrial fibrillation	Left cardiac atrium	Epigenomics	GSE62727
CVDS000068	Atrial fibrillation	Blood	Transcriptomics	GSE64904
CVDS000070	Atrial fibrillation	Right atrial appendage	Transcriptomics	GSE68475
CVDS000126	Atrial fibrillation	-	Genomics	GCST90204201

Showing 1 to 5 of 11 entries

Ancestry

Variant	Gene	Beta	Standard error	P value	Odds ratio	Study	Ancestry	Link

Tissue

Ancestry

Top genes selected

by median of PP.H4

by number of datasets

Gene	Tissue	Best coloc SNP	GWAS risk SNP	SNP.PP.H4	PP.H4.abf	Ancestry	Dataset

Link to PedAM: http://www.unimd.org/pedam/

Variant	Gene	Description	PMID

Variant	Pre miRNA	Region	Mature miRNA	ΔG	Predict	PMID

SNP	Reported disease	Gene	Description	PMID

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

Reported disease	Gene	Category	Description	Publication

Tissue/cell type	Gene	Reported disease	Alteration	log2FC	P value	Adjusted P value	Method	PMID

Genes with adjusted P value < 0.05 are included in plots.
Genes with |log2FC| > 1 and adjusted P value < 0.05 are considered as significant and are displayed in tables below.

Tissue

Top genes selected

by median of log2FC

by number of datasets

Tissue/cell type	Gene	Reported disease	Mapped disease	log2FC	P value	Adjusted P value	Method	Dataset

This panel displays associations of genes with Hypertension integrated from other databases.

About the 'Score': Q10: Detailed description of the RNADisease Scoring System

Gene type

Gene	Gene type	Species	Reported disease	Score	PMID	Gene link

Reported disease	Tissue	Gene	Effect size	P value	Method	Publication	PMID	Gene link

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

Reported disease	Gene	Category	Description	Publication

Reported disease	Gene	Species	Description	Publication

Only entries with adjusted p value <0.05 are displayed.

Name	Gene	Relation to gene	Tissue	Reported disease	Delta beta	P value	Adjusted P value	Dataset	GEO accession

Name	Gene	Relation to gene	Reported disease	Delta beta	P value	Adjusted P value	Tissue	PMID

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

Reported disease	Gene	Category	Description	Publication

Reported disease	Gene	Species	Description	Publication

Gene	Protein	Average log2FC	P value	Dataset

Metabolite	VIP	Dataset

About the Inference score: https://ctdbase.org/help/diseaseChemDetailHelp.jsp

Top chemicals selected

by number of publications

by average score

Chemical name	Chemical ID	Direct evidence	Reported disease	Inference gene	Inference score	#PMIDs	Gene link

Disease information

Gene prioritization

Dataset

GWAS significantly associated SNP

GWAS colocalization

Disease-variant association

Differentially expressed gene

Disease-gene association

Differentially methylated position

Disease-gene association

Differential expressed protein

Differentially expressed metabolite

Disease-chemical association