Gene

Symbol	CVD Atlas ID	Species	Gene ID	Biotype	Chr	Start	End
COX8A	CVDG006527	Homo sapiens	ENSG00000176340	Protein coding	11	63974620	63976543

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Disease or trait	Score
Systolic blood pressure	0.52349
Total cholesterol measurement	0.52349
Coronary atherosclerosis	0.40938
Critical limb ischemia	0.40938
Hypertension	0.40938

Showing 1 to 5 of 11 entries

Tissue/cell type	Disease	Condition 1	Condition 2	Alteration	log2FC	P value	Adjusted P value	Method	PMID

Genes with adjusted P value < 0.05 are included in plots.
Genes with |log2FC| > 1 and adjusted P value < 0.05 are considered as significant and are displayed in tables below.

Tissue

Top genes selected

by median of log2FC

by number of datasets

Dataset	Tissue/cell type	Reported disease	Mapped disease	log2FC	P value	Adjusted P value	Method	GEO accession

About the 'Score': Q10: Detailed description of the RNADisease Scoring System

Reported disease	Mapped disease	RNADisease score	PMID	Gene link

Reported disease/trait	Mapped trait	Tissue	Effect size	P value	Method	Publication	PMID	Gene link

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

Reported disease	Mapped disease	Category	Description	Publication

Reported disease	Mapped disease	Species	Description	Publication

Variant	Reported disease/trait	Mapped disease/trait	Beta	Standard error	P value	Odds ratio	Ancestry	Dataset	Link

Tissue

Ancestry

Reported disease/trait	Mapped disease/trait	Tissue	Best coloc SNP	GWAS risk SNP	SNP.PP.H4	PP.H4.abf	Ancestry	Dataset

Link to PedAM: http://www.unimd.org/pedam/

Variant	Reported disease	Mapped disease	Description	PMID

Variant	Disease	Pre miRNA	Region	Mature miRNA	△G	Exp	PMID

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

Reported disease	Gene	Category	Description	Publication

SNP	Reported disease	Mapped disease	Description	PMID

Name	Delta beta	P value	Adjusted P value	Reported disease	Mapped disease	Dataset

Name	Relation to gene	Delta beta	P value	Adjusted P value	Tissue	Reported disease	Mapped disease	Condition 1	Condition 2	PMID

Link to HMDD v4.0: https://www.cuilab.cn/hmdd

Reported disease	Mapped disease	Category	Description	Publication

Reported disease	Mapped disease	Species	Description	Publication

UniProt ID	Reported disease	Mapped disease	Average log2FC	P value	Dataset

Gene	PharmGKB gene ID	Chemical	PharmGKB chemical ID	Evidence	Association	PK/PD	PMID

About the Inference score: https://ctdbase.org/help/diseaseChemDetailHelp.jsp

Chemical name	Chemical ID	Reported disease	Mapped disease	Inference score	#PMIDs	Gene link

Gene information

Gene priorization

Gene ontology

Differentially expressed gene

Gene-disease association

GTEx expression level

GWAS significantly associated SNP

GWAS colocalization

Variant-disease association

Differentially methylated position

Gene-disease association

Differential expressed protein

Gene-chemical association