| URL: | http://bioinfo.au.tsinghua.edu.cn/member/jgu/oncomirdb/ |
| Full name: | A Database for Oncogenic & Tumor-Suppressive MicroRNAs |
| Description: | The oncomiRDB database aims at annotating the experimentally verified oncogenic and tumor-suppressive miRNAs from literature. |
| Year founded: | 2014 |
| Last update: | 2014-01-06 |
| Version: | |
| Accessibility: |
Unaccessible
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| Country/Region: | China |
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| University/Institution: | Tsinghua University |
| Address: | Beijing 100084, China |
| City: | Beijing |
| Province/State: | Beijing |
| Country/Region: | China |
| Contact name (PI/Team): | Jin Gu |
| Contact email (PI/Helpdesk): | jgu@tsinghua.edu.cn |
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OncomiRDB: a database for the experimentally verified oncogenic and tumor-suppressive microRNAs. [PMID: 24651967]
MicroRNAs (miRNAs), a class of small regulatory RNAs, play important roles in cancer initiation, progression and therapy. MiRNAs are found to regulate diverse cancer-related processes by targeting a large set of oncogenic and tumor-suppressive genes. To establish a high-confidence reference resource for studying the miRNA-regulated target genes and cellular processes in cancer, we manually curated 2259 entries of cancer-related miRNA regulations with direct experimental evidence from ?9000 abstracts, covering more than 300 miRNAs and 829 target genes across 25 cancer tissues. A web-based portal named oncomiRDB, which provides both graphical and text-based interfaces, was developed for easily browsing and searching all the annotations. It should be a useful resource for both the computational analysis and experimental study on miRNA regulatory networks and functions in cancer. http://bioinfo.au.tsinghua.edu.cn/oncomirdb/ jgu@tsinghua.edu.cn Supplementary data are available at Bioinformatics online. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com. |