| URL: | http://ir.hgc.jp/ |
| Full name: | Database and viewer of interacting regions (IRs) in protein sequences |
| Description: | IRView contains 3,417 IRs of human and mouse proteins obtained from several different sources, together with other functional region data, such as InterPro regions, non-synonymous (missense) single nucleotide polymorphisms (SNPs) and variant regions. |
| Year founded: | 2012 |
| Last update: | 2012-03-25 |
| Version: | 1 |
| Accessibility: |
Accessible
|
| Country/Region: | Japan |
| Data type: | |
| Data object: | |
| Database category: | |
| Major species: | |
| Keywords: |
| University/Institution: | University of Tokyo |
| Address: | Institute of Medical Science, The University of Tokyo, Tokyo 108-8039, Japan |
| City: | Tokyo |
| Province/State: | |
| Country/Region: | Japan |
| Contact name (PI/Team): | Etsuko Miyamoto-Sato |
| Contact email (PI/Helpdesk): | nekoneko@ims.u-tokyo.ac.jp |
|
IRView: a database and viewer for protein interacting regions. [PMID: 22592381]
Protein-protein interactions (PPIs) are mediated through specific regions on proteins. Some proteins have two or more protein interacting regions (IRs) and some IRs are competitively used for interactions with different proteins. IRView currently contains data for 3417 IRs in human and mouse proteins. The data were obtained from different sources and combined with annotated region data from InterPro. Information on non-synonymous single nucleotide polymorphism sites and variable regions owing to alternative mRNA splicing is also included. The IRView web interface displays all IR data, including user-uploaded data, on reference sequences so that the positional relationship between IRs can be easily understood. IRView should be useful for analyzing underlying relationships between the proteins behind the PPI networks. IRView is publicly available on the web at http://ir.hgc.jp/ |