| URL: | http://siRNA.cgb.ki.se |
| Full name: | |
| Description: | The siRNA database provides a gene-centric view of siRNA experimental data, including siRNAs of known efficacy and siRNAs predicted to be of high efficacy by a combination of methods. |
| Year founded: | 2005 |
| Last update: | 2015-01-01 |
| Version: | v1.0 |
| Accessibility: |
Unaccessible
|
| Country/Region: | Sweden |
| Data type: | |
| Data object: |
NA
|
| Database category: | |
| Major species: |
NA
|
| Keywords: |
| University/Institution: | Karolinska Institute |
| Address: | Berzelius väg 35, S-171 77 Stockholm, Sweden |
| City: | Stockholm |
| Province/State: | |
| Country/Region: | Sweden |
| Contact name (PI/Team): | Alistair M. Chalk |
| Contact email (PI/Helpdesk): | alistair.chalk@cgb.ki.se |
|
siRNAdb: a database of siRNA sequences. [PMID: 15608162]
Short interfering RNAs (siRNAs) are a popular method for gene-knockdown, acting by degrading the target mRNA. Before performing experiments it is invaluable to locate and evaluate previous knockdown experiments for the gene of interest. The siRNA database provides a gene-centric view of siRNA experimental data, including siRNAs of known efficacy and siRNAs predicted to be of high efficacy by a combination of methods. Linked to these sequences is information such as siRNA thermodynamic properties and the potential for sequence-specific off-target effects. The database enables the user to evaluate an siRNA's potential for inhibition and non-specific effects. The database is available at http://siRNA.cgb.ki.se. |