| URL: | http://compbio.mds.qmw.ac.uk/S4.html |
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| Description: | S4 is an automatically generated database of multiple structure-based sequence alignments of protein superfamilies in the SCOP database. |
| Year founded: | 2005 |
| Last update: | 2005-01-01 |
| Version: | v1.0 |
| Accessibility: |
Unaccessible
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| Country/Region: | United Kingdom |
| Data type: | |
| Data object: |
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| Database category: | |
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| Keywords: |
| University/Institution: | University of London |
| Address: | 32 Newark Street, London E1 2AA, UK |
| City: | London |
| Province/State: | |
| Country/Region: | United Kingdom |
| Contact name (PI/Team): | Mansoor A. S. Saqi |
| Contact email (PI/Helpdesk): | m.saqi@qmul.ac.uk |
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S4: structure-based sequence alignments of SCOP superfamilies. [PMID: 15608181]
S4 is an automatically generated database of multiple structure-based sequence alignments of protein superfamilies in the SCOP database. All structural domains that do not share more than 40% sequence identity as defined by the ASTRAL compendium of protein structures are included. The alignments are constructed using pairwise structural alignments to generate residue equivalences that are then integrated into multiple alignments using sequence alignment tools. We describe the database and give examples showing how the automatically generated S4 alignments compare favourably to hand-crafted alignments. Available at: http://compbio.mds.qmw.ac.uk/S4.html. |