| URL: | http://pisite.hgc.jp/ |
| Full name: | Database of Protein Interaction Sites |
| Description: | PiSITE is a web-based database of protein interaction sites. The PiSITE provides not only information of interaction sites of a protein from single PDB entry, but also information of interaction sites of a protein from multiple PDB entries including similar proteins. |
| Year founded: | 2009 |
| Last update: | 2009-01-01 |
| Version: | v1.0 |
| Accessibility: |
Accessible
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| Country/Region: | Japan |
| Data type: | |
| Data object: |
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| University/Institution: | University of Tokyo |
| Address: | 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan |
| City: | Tokyo |
| Province/State: | |
| Country/Region: | Japan |
| Contact name (PI/Team): | Kengo Kinoshita |
| Contact email (PI/Helpdesk): | kino@ims.u-tokyo.ac.jp |
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PiSite: a database of protein interaction sites using multiple binding states in the PDB. [PMID: 18836195]
The vast accumulation of protein structural data has now facilitated the observation of many different complexes in the PDB for the same protein. Therefore, a single protein complex is not sufficient to identify their interaction sites, especially for proteins with multiple binding states or different partners, such as hub proteins. PiSite is a database that provides protein-protein interaction sites at the residue level with consideration of multiple complexes at the same time, by mapping the binding sites of all complexes containing the same protein in the PDB. PiSite provides easy web interfaces with an interactive viewer working with typical web browsers, and the different binding modes can be checked visually. All of the information can also be downloaded for further analyses. In addition, PiSite provides a list of proteins with multiple binding partners and multiple binding states, as well as up-to-date statistics of protein-protein interfaces. PiSite is available at http://pisite.hgc.jp. |