| URL: | http://horfdb.dfci.harvard.edu |
| Full name: | human ORFeome version 3.1 |
| Description: | human ORFeome version 3.1 (hORFeome v3.1), currently the largest publicly available resource of full-length human ORFs which contains 12,212 ORFs, representing 10,214 human genes, and corresponds to a 51% expansion of the original hORFeome v1.1. |
| Year founded: | 2007 |
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| Accessibility: |
Accessible
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| Country/Region: | United States |
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| University/Institution: | Harvard University |
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| Country/Region: | United States |
| Contact name (PI/Team): | Marc Vidal |
| Contact email (PI/Helpdesk): | marc_vidal@dfci.harvard.edu |
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hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. [PMID: 17207965]
Complete sets of cloned protein-encoding open reading frames (ORFs), or ORFeomes, are essential tools for large-scale proteomics and systems biology studies. Here we describe human ORFeome version 3.1 (hORFeome v3.1), currently the largest publicly available resource of full-length human ORFs (available at ). Generated by Gateway recombinational cloning, this collection contains 12,212 ORFs, representing 10,214 human genes, and corresponds to a 51% expansion of the original hORFeome v1.1. An online human ORFeome database, hORFDB, was built and serves as the central repository for all cloned human ORFs (http://horfdb.dfci.harvard.edu). This expansion of the original ORFeome resource greatly increases the potential experimental search space for large-scale proteomics studies, which will lead to the generation of more comprehensive datasets. |