Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database Profile

General information

URL: http://angiogenes.kbrin.louisville.edu
Full name: ANGIOGENES
Description: ANGIOGENES is a tool to explore and compare the expression profiles of transcripts in endothelial cells.
Year founded: 2016
Last update: 2017
Version:
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Country/Region: United States
Data type:
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Contact information

University/Institution: University of Louisville
Address: Cardiovascular Innovation Institute University of Louisville 302 E Muhammad Ali Blvd Louisville, KY 40202, United States
City: Louisville
Province/State: Kentucky
Country/Region: United States
Contact name (PI/Team): Shizuka Uchida
Contact email (PI/Helpdesk): heart.lncrna@gmail.com

Publications

27582018
ANGIOGENES: knowledge database for protein-coding and noncoding RNA genes in endothelial cells. [PMID: 27582018]
Müller R, Weirick T, John D, Militello G, Chen W, Dimmeler S, Uchida S.

Increasing evidence indicates the presence of long noncoding RNAs (lncRNAs) is specific to various cell types. Although lncRNAs are speculated to be more numerous than protein-coding genes, the annotations of lncRNAs remain primitive due to the lack of well-structured schemes for their identification and description. Here, we introduce a new knowledge database "ANGIOGENES" (http://angiogenes.uni-frankfurt.de) to allow for in silico screening of protein-coding genes and lncRNAs expressed in various types of endothelial cells, which are present in all tissues. Using the latest annotations of protein-coding genes and lncRNAs, publicly-available RNA-seq data was analyzed to identify transcripts that are expressed in endothelial cells of human, mouse and zebrafish. The analyzed data were incorporated into ANGIOGENES to provide a one-stop-shop for transcriptomics data to facilitate further biological validation. ANGIOGENES is an intuitive and easy-to-use database to allow in silico screening of expressed, enriched and/or specific endothelial transcripts under various conditions. We anticipate that ANGIOGENES serves as a starting point for functional studies to elucidate the roles of protein-coding genes and lncRNAs in angiogenesis.

Sci Rep. 2016:6() | 13 Citations (from Europe PMC, 2021-06-19)

Ranking

All databases:
2343/5061 (53.725%)
Expression:
456/924 (50.758%)
2343
Total Rank
13
Citations
2.6
z-index

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Record metadata

Created on: 2018-01-27
Curated by:
[2018-11-30]
Farah Nazir [2018-04-05]