| URL: | http://www.moseslab.csb.utoronto.ca/KID |
| Full name: | Yeast Kinase Interaction Database |
| Description: | KID contains high- and low-throughput data relevant to phosphorylation events. KID includes 6,225 low-throughput and 21,990 high-throughput interactions, from greater than 35,000 experiments. |
| Year founded: | 2011 |
| Last update: | 2017 |
| Version: | |
| Accessibility: |
Accessible
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| Country/Region: | Canada |
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| University/Institution: | University of Toronto |
| Address: | Department of Molecular Genetics, The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto,160 College Street, Toronto, M3S 3E1, Canada |
| City: | Toronto |
| Province/State: | |
| Country/Region: | Canada |
| Contact name (PI/Team): | Brenda J Andrews |
| Contact email (PI/Helpdesk): | brenda.andrews@utoronto.ca |
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A quantitative literature-curated gold standard for kinase-substrate pairs. [PMID: 21492431]
We describe the Yeast Kinase Interaction Database (KID, http://www.moseslab.csb.utoronto.ca/KID/), which contains high- and low-throughput data relevant to phosphorylation events. KID includes 6,225 low-throughput and 21,990 high-throughput interactions, from greater than 35,000 experiments. By quantitatively integrating these data, we identified 517 high-confidence kinase-substrate pairs that we consider a gold standard. We show that this gold standard can be used to assess published high-throughput datasets, suggesting that it will enable similar rigorous assessments in the future. |