| URL: | http://www.pkdb.ifsc.usp.br |
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| Description: | The study of pharmacokinetic properties (PK) is of great importance in drug discovery and development. In the present work, PK/DB (a new freely available database for PK) was designed with the aim of creating robust databases for pharmacokinetic studies and in silico absorption, distribution, metabolism and excretion (ADME) prediction. Comprehensive, web-based and easy to access, PK/DB manages 1203 compounds which represent 2973 pharmacokinetic measurements, including five models for in silico ADME prediction (human intestinal absorption, human oral bioavailability, plasma protein binding, blood-brain barrier and water solubility). |
| Year founded: | 2008 |
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| Accessibility: |
Accessible
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| Country/Region: | Brazil |
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| Major species: |
NA
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| University/Institution: | University of São Paulo |
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| Country/Region: | Brazil |
| Contact name (PI/Team): | Adriano D. Andricopulo |
| Contact email (PI/Helpdesk): | aandrico@if.sc.usp.br |
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PK/DB: database for pharmacokinetic properties and predictive in silico ADME models. [PMID: 18684738]
The study of pharmacokinetic properties (PK) is of great importance in drug discovery and development. In the present work, PK/DB (a new freely available database for PK) was designed with the aim of creating robust databases for pharmacokinetic studies and in silico absorption, distribution, metabolism and excretion (ADME) prediction. Comprehensive, web-based and easy to access, PK/DB manages 1203 compounds which represent 2973 pharmacokinetic measurements, including five models for in silico ADME prediction (human intestinal absorption, human oral bioavailability, plasma protein binding, blood-brain barrier and water solubility). |