Database Commons

a catalog of biological databases

e.g., animal; RNA; Methylation; China

Database Profile

General information

URL: http://bidd2.nus.edu.sg/herod/index.php
Full name: human ethnic and regional specific omics database
Description: Genetic and gene expression variations within and between populations and across regions have profound effects on the biological phenotypes, diseases and disease prevalence, and therapeutic response. The precision medicines can be facilitated by the study of the patient data of specific ethnicity and region of residence. However, there is a lack of facility for broadly and conveniently accessing the relevant data. Therefore, we introduced a new database, HEROD, a human ethnic and regional specific OMICS database, for convenient access of the Omics data of patients of 169 diseases in 7 ethnic populations from 193 cities/provinces of 49 nations/regions.
Year founded: 2017
Last update:
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Country/Region: Singapore
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Contact information

University/Institution: National University of Singapore
Address: Bioinformatics and Drug Design Group, Department of Pharmacy, National University of Singapore, Singapore 117543
City:
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Country/Region: Singapore
Contact name (PI/Team): Yu Zong Chen
Contact email (PI/Helpdesk): phacyz@nus.edu.sg

Publications

28549078
HEROD: a human ethnic and regional specific omics database. [PMID: 28549078]
Zeng X, Tao L, Zhang P, Qin C, Chen S, He W, Tan Y, Xia Liu H, Yang SY, Chen Z, Jiang YY, Chen YZ.

Motivation: Genetic and gene expression variations within and between populations and across geographical regions have substantial effects on the biological phenotypes, diseases, and therapeutic response. The development of precision medicines can be facilitated by the OMICS studies of the patients of specific ethnicity and geographic region. However, there is an inadequate facility for broadly and conveniently accessing the ethnic and regional specific OMICS data.
Results: Here, we introduced a new free database, HEROD, a human ethnic and regional specific OMICS database. Its first version contains the gene expression data of 53?070 patients of 169 diseases in seven ethnic populations from 193 cities/regions in 49 nations curated from the Gene Expression Omnibus (GEO), the ArrayExpress Archive of Functional Genomics Data (ArrayExpress), the Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC). Geographic region information of curated patients was mainly manually extracted from referenced publications of each original study. These data can be accessed and downloaded via keyword search, World map search, and menu-bar search of disease name, the international classification of disease code, geographical region, location of sample collection, ethnic population, gender, age, sample source organ, patient type (patient or healthy), sample type (disease or normal tissue) and assay type on the web interface.
Availability and implementation: The HEROD database is freely accessible at http://bidd2.nus.edu.sg/herod/index.php. The database and web interface are implemented in MySQL, PHP and HTML with all major browsers supported.
Contact: phacyz@nus.edu.sg.

Bioinformatics. 2017:33(20) | 1 Citations (from Europe PMC, 2021-06-19)

Ranking

All databases:
4775/5061 (5.671%)
Health and medicine:
1012/1067 (5.248%)
Metadata:
467/497 (6.237%)
4775
Total Rank
1
Citations
0.25
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Record metadata

Created on: 2018-01-28
Curated by:
Fatima Batool [2018-04-12]
Yang Zhang [2018-01-27]