| URL: | http://mgdd.pasteur.ma |
| Full name: | Moroccan Genetic Disease Database |
| Description: | Home The Moroccan Genetic Disease Database (MGDD) collect and document mutations and frequencies of polymorphisms reported in the Moroccan population. The information in the MGDD allow researchers and clinicians to find mutations associated to a given disease or gene of interest, and they can also find polymorphisms associated with susceptibility to a genetic disease or individual responses to pharmaceutical drugs or environmental factors. |
| Year founded: | 2014 |
| Last update: | 17/9/2016 |
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| Accessibility: |
Accessible
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| Country/Region: | Morocco |
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| University/Institution: | Pasteur Institute of Morocco |
| Address: | Laboratory of Human Molecular Genetics, Department of Scientific Research, Pasteur Institute of Morocco, Casablanca, Morocco. |
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| Country/Region: | Morocco |
| Contact name (PI/Team): | Omar Abidi |
| Contact email (PI/Helpdesk): | abidi.or@gmail.com |
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The Moroccan Genetic Disease Database (MGDD): a database for DNA variations related to inherited disorders and disease susceptibility. [PMID: 23860041]
National and ethnic mutation databases provide comprehensive information about genetic variations reported in a population or an ethnic group. In this paper, we present the Moroccan Genetic Disease Database (MGDD), a catalogue of genetic data related to diseases identified in the Moroccan population. We used the PubMed, Web of Science and Google Scholar databases to identify available articles published until April 2013. The Database is designed and implemented on a three-tier model using Mysql relational database and the PHP programming language. To date, the database contains 425 mutations and 208 polymorphisms found in 301 genes and 259 diseases. Most Mendelian diseases in the Moroccan population follow autosomal recessive mode of inheritance (74.17%) and affect endocrine, nutritional and metabolic physiology. The MGDD database provides reference information for researchers, clinicians and health professionals through a user-friendly Web interface. Its content should be useful to improve researches in human molecular genetics, disease diagnoses and design of association studies. MGDD can be publicly accessed at http://mgdd.pasteur.ma. |