| URL: | http://pranag.physics.iisc.ernet.in/SPGDB |
| Full name: | Streptococcus pneumoniae Genome Database |
| Description: | The Streptococcus pneumoniae Genome database (SPGDB) is an integrated database containing the genomic and proteomic information of the entire S. pneumoniae strains. The aim of this database is to afford a resource for the research community to perform varied searches against S. pneumoniae strains. The database has the inbuilt tools like BLAST, DNA motif search, the graphics based plugin, GBrowse and Jmol to visualize the genome and Protein Data Bank (PDB) structures of S. pneumoniae strains respectively. In addition, the database provides the users to browse all annotations using either the simple or advanced Boolean based search tools. The database covers the significant points on general and cultutal characteristics, virulence factors, pathogenic mechanism and laboratory diagnosis of S. pneumoniae. A superior understanding of the genes accountable for virulence in these strains can facilitate researchers determine immunogen targets and drug candidates. |
| Year founded: | 2014 |
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| Accessibility: |
Accessible
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| Country/Region: | India |
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| University/Institution: | VIT University |
| Address: | Medical & Biological Computing Laboratory, School of Biosciences and Technology, VIT University, Vellore 632 014, India |
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| Country/Region: | India |
| Contact name (PI/Team): | Anbarasu A |
| Contact email (PI/Helpdesk): | aanand@vit.ac.in |
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Streptococcus pneumoniae Genome Database (SPGDB): a database for strain specific comparative analysis of Streptococcus pneumoniae genes and proteins. [PMID: 25269378]
Streptococcus pneumoniae causes pneumonia, septicemia and meningitis. S. pneumoniae is responsible for significant mortality both in children and in the elderly. In recent years, the whole genome sequencing of various S. pneumoniae strains have increased manifold and there is an urgent need to provide organism specific annotations to the scientific community. This prompted us to develop the Streptococcus pneumoniae Genome Database (SPGDB) to integrate and analyze the completely sequenced and available S. pneumoniae genome sequences. Further, links to several tools are provided to compare the pool of gene and protein sequences, and proteins structure across different strains of S. pneumoniae. SPGDB aids in the analysis of phenotypic variations as well as to perform extensive genomics and evolutionary studies with reference to S. pneumoniae. The database will be updated at regular intervals and is freely accessible through the URL: http://pranag.physics.iisc.ernet.in/SPGDB/. |