| URL: | http://www.baamps.it |
| Full name: | biofilm-active AMPs database |
| Description: | BaAMPs (Biofilm-active AMPs) is a database designed with the key objective of collecting data on AMPs specifically tested against microbial biofilms in an exhaustive and detailed manner. The aim of this project is to provide useful resources for the study of AMPs against biofilms to microbiologist, bioinformatics researcher and medical scientist working in this field in an open-access framework. |
| Year founded: | 2015 |
| Last update: | 2017 |
| Version: | |
| Accessibility: |
Accessible
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| Country/Region: | Italy |
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| University/Institution: | Nanoscience Institute-CNR and SNS |
| Address: | NEST, Nanoscience Institute-CNR and SNS, Pisa , Italy. |
| City: | Pisa |
| Province/State: | |
| Country/Region: | Italy |
| Contact name (PI/Team): | Mariagrazia Di Luca |
| Contact email (PI/Helpdesk): | mariagrazia.diluca@nano.cnr.it |
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BaAMPs: the database of biofilm-active antimicrobial peptides. [PMID: 25760404]
Antimicrobial peptides (AMPs) are increasingly being considered as novel agents against biofilms. The development of AMP-based anti-biofilm strategies strongly relies on the design of sequences optimized to target specific features of sessile bacterial/fungal communities. Although several AMP databases have been created and successfully exploited for AMP design, all of these use data collected on peptides tested against planktonic microorganisms. Here, an open-access, manually curated database of AMPs specifically assayed against microbial biofilms (BaAMPs) is presented for the first time. In collecting relevant data from the literature an effort was made to define a minimal standard set of essential information including, for each AMP, the microbial species and biofilm conditions against which it was tested, and the specific assay and peptide concentration used. The availability of these data in an organized framework will benefit anti-biofilm research and support the design of novel molecules active against biofilm. BaAMPs is accessible at http://www.baamps.it. |