| URL: | http://tanlab.ucdenver.edu/DSigDB |
| Full name: | Drug SIGnatures DataBase |
| Description: | Drug Signatures Database (DSigDB) is a new gene set resource that relates drugs/compounds and their target genes, for gene set enrichment analysis (GSEA). DSigDB currently holds 22 527 gene sets, consists of 17 389 unique compounds covering 19 531 genes. |
| Year founded: | 2015 |
| Last update: | |
| Version: | 1 |
| Accessibility: |
Accessible
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| Country/Region: | United States |
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| University/Institution: | University of Colorado at Denver and Health Sciences Center |
| Address: | Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora 80045, CO, USA |
| City: | Aurora |
| Province/State: | CO |
| Country/Region: | United States |
| Contact name (PI/Team): | Aik Choon Tan |
| Contact email (PI/Helpdesk): | aikchoon.tan@ucdenver.edu |
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DSigDB: drug signatures database for gene set analysis. [PMID: 25990557]
We report the creation of Drug Signatures Database (DSigDB), a new gene set resource that relates drugs/compounds and their target genes, for gene set enrichment analysis (GSEA). DSigDB currently holds 22?527 gene sets, consists of 17?389 unique compounds covering 19?531 genes. We also developed an online DSigDB resource that allows users to search, view and download drugs/compounds and gene sets. DSigDB gene sets provide seamless integration to GSEA software for linking gene expressions with drugs/compounds for drug repurposing and translational research. |