| URL: | http://www.unimd.org/pedam |
| Full name: | Pediatric Disease Annotations & Medicines |
| Description: | PedAM contains standardized 8,528 pediatric disease terms (containing 4,542 unique disease concepts and 3,986 synonyms) with 8 annotation fields for each disease, including definition synonyms, gene, symptom, cross-reference (Xref), human phenotypes, and its corresponding phenotypes in the mouse (MPO). |
| Year founded: | 2018 |
| Last update: | |
| Version: | 2.0 |
| Accessibility: |
Accessible
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| Country/Region: | China |
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| Data object: | |
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| University/Institution: | East China Normal University |
| Address: | The Center for Bioinformatics and Computational Biology, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai 200241, China |
| City: | Shanghai |
| Province/State: | Shanghai |
| Country/Region: | China |
| Contact name (PI/Team): | Tieliu Shi |
| Contact email (PI/Helpdesk): | tlshi@bio.ecnu.edu.cn |
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PedAM: a database for Pediatric Disease Annotation and Medicine. [PMID: 29126123]
There is a significant number of children around the world suffering from the consequence of the misdiagnosis and ineffective treatment for various diseases. To facilitate the precision medicine in pediatrics, a database namely the Pediatric Disease Annotations & Medicines (PedAM) has been built to standardize and classify pediatric diseases. The PedAM integrates both biomedical resources and clinical data from Electronic Medical Records to support the development of computational tools, by which enables robust data analysis and integration. It also uses disease-manifestation (D-M) integrated from existing biomedical ontologies as prior knowledge to automatically recognize text-mined, D-M-specific syntactic patterns from 774 514 full-text articles and 8 848 796 abstracts in MEDLINE. Additionally, disease connections based on phenotypes or genes can be visualized on the web page of PedAM. Currently, the PedAM contains standardized 8528 pediatric disease terms (4542 unique disease concepts and 3986 synonyms) with eight annotation fields for each disease, including definition synonyms, gene, symptom, cross-reference (Xref), human phenotypes and its corresponding phenotypes in the mouse. The database PedAM is freely accessible at http://www.unimd.org/pedam/. |